User profiles for Ashok Thillaisundaram
Ashok ThillaisundaramMicrosoft Research Verified email at microsoft.com Cited by 1072 |
Accurate structure prediction of biomolecular interactions with AlphaFold 3
…, P Savy, S Singh, A Stecula, A Thillaisundaram…�- Nature, 2024 - nature.com
The introduction of AlphaFold 2 1 has spurred a revolution in modelling the structure of
proteins and their interactions, enabling a huge range of applications in protein modelling and …
proteins and their interactions, enabling a huge range of applications in protein modelling and …
Biomedical relation extraction with pre-trained language representations and minimal task-specific architecture
A Thillaisundaram, T Togia�- arXiv preprint arXiv:1909.12411, 2019 - arxiv.org
This paper presents our participation in the AGAC Track from the 2019 BioNLP Open Shared
Tasks. We provide a solution for Task 3, which aims to extract "gene - function change - …
Tasks. We provide a solution for Task 3, which aims to extract "gene - function change - …
De novo design of high-affinity protein binders with AlphaProteo
…, RG Schneider, D Saxton, A Thillaisundaram…�- arXiv preprint arXiv�…, 2024 - arxiv.org
Computational design of protein-binding proteins is a fundamental capability with broad
utility in biomedical research and biotechnology. Recent methods have made strides against …
utility in biomedical research and biotechnology. Recent methods have made strides against …
Constructing large scale biomedical knowledge bases from scratch with rapid annotation of interpretable patterns
Knowledge base construction is crucial for summarising, understanding and inferring
relationships between biomedical entities. However, for many practical applications such as drug …
relationships between biomedical entities. However, for many practical applications such as drug …
A Hierarchical Transformer for Unsupervised Parsing
A Thillaisundaram�- arXiv preprint arXiv:2003.13841, 2020 - arxiv.org
The underlying structure of natural language is hierarchical; words combine into phrases,
which in turn form clauses. An awareness of this hierarchical structure can aid machine …
which in turn form clauses. An awareness of this hierarchical structure can aid machine …
Signatures of Brane Inflation
A Thillaisundaram�- arXiv preprint arXiv:1208.1042, 2012 - arxiv.org
We study slow-roll inflation on a three-brane in a five-dimensional bulk where the effects of
energy loss from the brane due to graviton emission is included in a self-consistent manner. …
energy loss from the brane due to graviton emission is included in a self-consistent manner. …
Aspects of fluid dynamics and the fluid/gravity correspondence
A Thillaisundaram - 2017 - repository.cam.ac.uk
This thesis considers various extensions to the fluid/gravity correspondence as well as
problems fundamental to the study of fluid dynamics. The fluid/gravity correspondence is a map …
problems fundamental to the study of fluid dynamics. The fluid/gravity correspondence is a map …
[PDF][PDF] Topics in High-dimensional and Large-scale Data Analysis
RD Shah - 2014 - Citeseer
The problem of variable selection has received a huge amount of attention over the last 15
years, motivated by the desire to understand structure in massive datasets that are now …
years, motivated by the desire to understand structure in massive datasets that are now …
Learning to extend molecular scaffolds with structural motifs
Recent advancements in deep learning-based modeling of molecules promise to accelerate
in silico drug discovery. A plethora of generative models is available, building molecules …
in silico drug discovery. A plethora of generative models is available, building molecules …
The contact property for magnetic flows on surfaces
G Benedetti�- arXiv preprint arXiv:1805.04916, 2018 - arxiv.org
This is the author's PhD Thesis (University of Cambridge, 2014) in its original form. In the
first part, using an invariance result, we compute the symplectic homology of contact-type …
first part, using an invariance result, we compute the symplectic homology of contact-type …