Actively personalized vaccination trial for newly diagnosed glioblastoma
Patients with glioblastoma currently do not sufficiently benefit from recent breakthroughs in
cancer treatment that use checkpoint inhibitors 1 , 2 . For treatments using checkpoint …
cancer treatment that use checkpoint inhibitors 1 , 2 . For treatments using checkpoint …
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
C Yokoyama, X Wang, MR Briggs, A Admon, J Wu…�- Cell, 1993 - cell.com
Sterol regulatory element 1 (SRE-1), a decamer (5′-ATC-ACCCCAC-3′) flanking the low
density lipoprotein (LDL) receptor gene, activates transcription in sterol-depleted cells and is …
density lipoprotein (LDL) receptor gene, activates transcription in sterol-depleted cells and is …
Human Proto-Oncogene c-jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1
D Bohmann, TJ Bos, A Admon, T Nishimura, PK Vogt…�- Science, 1987 - science.org
Nuclear oncogene products have the potential to induce alterations in gene regulation leading
to the genesis of cancer. The biochemical mechanisms by which nuclear oncoproteins …
to the genesis of cancer. The biochemical mechanisms by which nuclear oncoproteins …
[HTML][HTML] The biogenesis of the immunopeptidome
A Admon�- Seminars in Immunology, 2023 - Elsevier
The immunopeptidome is the repertoire of peptides bound and presented by the MHC class
I, class II, and non-classical molecules. The peptides are produced by the degradation of …
I, class II, and non-classical molecules. The peptides are produced by the degradation of …
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core�…
HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated
advantages and limitations of many depletion, fractionation, and MS technology platforms; (…
advantages and limitations of many depletion, fractionation, and MS technology platforms; (…
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
…, H Zhang, N Divecha, MA Connelly, A Admon…�- Cell, 1995 - cell.com
DNA-dependent protein kinase (DNA-PK), which is involved in DNA double-stranded break
repair and V (D) J recombination, comprises a DNA-targeting component called Ku and an-…
repair and V (D) J recombination, comprises a DNA-targeting component called Ku and an-…
Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins
HM Jantzen, A Admon, SP Bell, R Tjian�- Nature, 1990 - nature.com
The eukaryotic upstream binding factor (DBF), recognizes the ribosomal RNA gene
promoter and activates transcription mediated by RNA poly-merase I through cooperative …
promoter and activates transcription mediated by RNA poly-merase I through cooperative …
NF-AT components define a family of transcription factors targeted in T-cell activation
THE NF-AT transcription complex 1 is required for the expression of a group of proteins that
collectively coordinate the immune response 2–4 . Here we purify two proteins encoded by …
collectively coordinate the immune response 2–4 . Here we purify two proteins encoded by …
[HTML][HTML] A novel site for ubiquitination: the N‐terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein
The ubiquitin proteolytic pathway is a major system for selective protein degradation in
eukaryotic cells. One of the first steps in the degradation of a protein via this pathway involves …
eukaryotic cells. One of the first steps in the degradation of a protein via this pathway involves …
[HTML][HTML] The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
The ubiquitin-proteasome pathway plays a crucial role in many cellular processes by degrading
substrates tagged by polyubiquitin chains, linked mostly through lysine 48 of ubiquitin. …
substrates tagged by polyubiquitin chains, linked mostly through lysine 48 of ubiquitin. …