Application of a semi-automatic algorithm for identification of molecular components in SBML models

A Maggiolo-Schettini, P Milazzo, G Pardini�- arXiv preprint arXiv�…, 2013 - arxiv.org
A Maggiolo-Schettini, P Milazzo, G Pardini
arXiv preprint arXiv:1309.7689, 2013arxiv.org
Reactions forming a pathway can be rewritten by making explicit the different molecular
components involved in them. A molecular component represents a biological entity (eg a
protein) in all its states (free, bound, degraded, etc.). In this paper we show the application of
a component identification algorithm to a number of real-world models to experimentally
validate the approach. Components identification allows subpathways to be computed to
better understand the pathway functioning.
Reactions forming a pathway can be rewritten by making explicit the different molecular components involved in them. A molecular component represents a biological entity (e.g. a protein) in all its states (free, bound, degraded, etc.). In this paper we show the application of a component identification algorithm to a number of real-world models to experimentally validate the approach. Components identification allows subpathways to be computed to better understand the pathway functioning.
arxiv.org
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