Nowadays, there is a growing agreement that sustainable mobility is about effectively interconnecting transport systems which have to provide a door-to-door service. Intermodal transportation of freights is an important issue in this context, due to the increasing amount of freight movements all over the world. The current study proposes and examines an approach for optimizing such transport chains. In this approach, the freight distribution corridor is decomposed into the different elements with individual functions that interact two-by-two based on a cooperative scheme relying on information flow in the corridor. The methodology is evaluated by means of an example corridor and the results are presented.