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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1978 2
1979 19
1980 78
1981 71
1982 131
1983 124
1984 150
1985 264
1986 400
1987 558
1988 735
1989 947
1990 1108
1991 1173
1992 829
1993 455
1994 507
1995 535
1996 533
1997 590
1998 590
1999 645
2000 606
2001 660
2002 650
2003 635
2004 663
2005 628
2006 654
2007 684
2008 649
2009 679
2010 715
2011 634
2012 625
2013 667
2014 695
2015 737
2016 824
2017 874
2018 841
2019 870
2020 943
2021 1035
2022 1189
2023 1174
2024 777
2025 5

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27,959 results

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Page 1
T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.
Lee DW, Kochenderfer JN, Stetler-Stevenson M, Cui YK, Delbrook C, Feldman SA, Fry TJ, Orentas R, Sabatino M, Shah NN, Steinberg SM, Stroncek D, Tschernia N, Yuan C, Zhang H, Zhang L, Rosenberg SA, Wayne AS, Mackall CL. Lee DW, et al. Lancet. 2015 Feb 7;385(9967):517-528. doi: 10.1016/S0140-6736(14)61403-3. Epub 2014 Oct 13. Lancet. 2015. PMID: 25319501 Free PMC article. Clinical Trial.
Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor.
Zhang J, Li J, Hou Y, Lin Y, Zhao H, Shi Y, Chen K, Nian C, Tang J, Pan L, Xing Y, Gao H, Yang B, Song Z, Cheng Y, Liu Y, Sun M, Linghu Y, Li J, Huang H, Lai Z, Zhou Z, Li Z, Sun X, Chen Q, Su D, Li W, Peng Z, Liu P, Chen W, Huang H, Chen Y, Xiao B, Ye L, Chen L, Zhou D. Zhang J, et al. Cell. 2024 Jun 20;187(13):3409-3426.e24. doi: 10.1016/j.cell.2024.04.023. Epub 2024 May 13. Cell. 2024. PMID: 38744281
Chimeric antigen receptor T cells for sustained remissions in leukemia.
Maude SL, Frey N, Shaw PA, Aplenc R, Barrett DM, Bunin NJ, Chew A, Gonzalez VE, Zheng Z, Lacey SF, Mahnke YD, Melenhorst JJ, Rheingold SR, Shen A, Teachey DT, Levine BL, June CH, Porter DL, Grupp SA. Maude SL, et al. N Engl J Med. 2014 Oct 16;371(16):1507-17. doi: 10.1056/NEJMoa1407222. N Engl J Med. 2014. PMID: 25317870 Free PMC article. Clinical Trial.
CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.
Turtle CJ, Hanafi LA, Berger C, Gooley TA, Cherian S, Hudecek M, Sommermeyer D, Melville K, Pender B, Budiarto TM, Robinson E, Steevens NN, Chaney C, Soma L, Chen X, Yeung C, Wood B, Li D, Cao J, Heimfeld S, Jensen MC, Riddell SR, Maloney DG. Turtle CJ, et al. J Clin Invest. 2016 Jun 1;126(6):2123-38. doi: 10.1172/JCI85309. Epub 2016 Apr 25. J Clin Invest. 2016. PMID: 27111235 Free PMC article. Clinical Trial.
NLGN4X TCR transgenic T cells to treat gliomas.
Krämer C, Kilian M, Chih YC, Kourtesakis A, Hoffmann DC, Boschert T, Koopmann P, Sanghvi K, De Roia A, Jung S, Jähne K, Day B, Shultz LD, Ratliff M, Harbottle R, Green EW, Will R, Wick W, Platten M, Bunse L. Krämer C, et al. Neuro Oncol. 2024 Feb 2;26(2):266-278. doi: 10.1093/neuonc/noad172. Neuro Oncol. 2024. PMID: 37715782 Free PMC article.
A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma.
Zhu W, Zhang Z, Chen J, Chen X, Huang L, Zhang X, Huang X, Ma N, Xu W, Yi X, Lu X, Fu X, Li S, Mo G, Wang Y, Yuan G, Zang M, Li Q, Jiang X, He Y, Wu S, He Y, Li Y, Hou J. Zhu W, et al. Signal Transduct Target Ther. 2024 Apr 20;9(1):101. doi: 10.1038/s41392-024-01792-6. Signal Transduct Target Ther. 2024. PMID: 38643203 Free PMC article.
27,959 results
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