Transcriptional autoregulation of the proto-oncogene fos
- PMID: 2839774
- DOI: 10.1038/334314a0
Transcriptional autoregulation of the proto-oncogene fos
Abstract
Serum-induced transcription of the proto-oncogene fos is under negative feedback regulation mediated by the fos protein. The fos promoter region responsive to repression is also required for serum inducibility and binds a nucleoprotein complex in which the nuclear factor AP-1 is associated with fos protein.
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