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Confocal Raman Spectroscopy Coupled With In Vitro Permeation Testing To Study The Effects Of Formalin Fixation On The Skin Barrier Function Of Reconstructed Human Epidermis, Hichem Kichou, Franck Bonnier, Amanda C. Caritá, Hugh Byrne, Igor Choupra, Emilie Munnier 2024 UPR CNRS 4301 CBM, département NMNS « NanoMédicaments et NanoSondes », Université de Tours, 31 avenue Monge, 37200 Tours.

Confocal Raman Spectroscopy Coupled With In Vitro Permeation Testing To Study The Effects Of Formalin Fixation On The Skin Barrier Function Of Reconstructed Human Epidermis, Hichem Kichou, Franck Bonnier, Amanda C. Caritá, Hugh Byrne, Igor Choupra, Emilie Munnier

Articles

Confocal Raman Spectroscopy is recognised as a potent tool for molecular characterisation of biological specimens. There is a growing demand for In Vitro Permeation Tests (IVPT) in the pharmaceutical and cosmetic areas, increasingly conducted using Reconstructed Human Epidermis (RHE) skin models. In this study, chemical fixation of RHE in 10% Neutral Buffered Formalin for 24 hours has been examined for storing RHE samples at 4°C for up to 21 days. Confocal Raman Spectroscopy, combined with Principal Components Analysis, revealed the molecular-level effects of fixation, notably in protein and lipid conformation within the stratum corneum and viable epidermis. IVPT by means …


Gas Chromatography-Mass Spectrometry (Gc-Ms), Computational Analysis, And In Vitro Effect Of Essential Oils From Two Aromatic Plants, Bubonium Graveolens And Launaea Arborescens Growing In Southwest Algeria Against Potato Cyst Nematodes, Souad Ziane, Chaouki Selles, Khaldun M. Al Azzam, Bounoua Nadia, Belal O. Al-Najjar, Ali Al-Samydai, Obada A. Sibai, El-Sayed Negim 2024 Laboratory of Natural and Bioactive Substances (LASNABIO), Department of Chemistry, Tlemcen, Algeria

Gas Chromatography-Mass Spectrometry (Gc-Ms), Computational Analysis, And In Vitro Effect Of Essential Oils From Two Aromatic Plants, Bubonium Graveolens And Launaea Arborescens Growing In Southwest Algeria Against Potato Cyst Nematodes, Souad Ziane, Chaouki Selles, Khaldun M. Al Azzam, Bounoua Nadia, Belal O. Al-Najjar, Ali Al-Samydai, Obada A. Sibai, El-Sayed Negim

Karbala International Journal of Modern Science

The study tested the nematicidal effects of essential oils from Bubonium graveolens and Launaea arborescens on the potato cyst nematode Globodera rostochiens. The chemical composition of the essential oils was analyzed using GC-MS. To determine the concentration that killed 50% of the nematode population (LC50), five concentrations of the essential oils were applied to the tested organisms. The effects of essential oils on the hatching of cyst nematode (Globodera rostochiensis sp.) eggs in vitro demonstrated a wide variety of effects ranging from no impact to mild, moderate, and strong effects, which increased dramatically with exposure duration and concentration. All the …


Broken Su(3) Description Of Energy Levels And Decay Properties In Gadolinium Isotopes (A=156-160), Fahmi Sh. Radhi, Amir Abdul Ameer Mohammed Ali Dr., Ali H. Al-Musawi 2024 Mechanical Power Engineering Techniques Department, Shatt Al-Arab University College, Basra, Iraq

Broken Su(3) Description Of Energy Levels And Decay Properties In Gadolinium Isotopes (A=156-160), Fahmi Sh. Radhi, Amir Abdul Ameer Mohammed Ali Dr., Ali H. Al-Musawi

Karbala International Journal of Modern Science

This study presents an in-depth examination of the energy levels and decay properties of Gadolinium (Gd) isotopes with mass numbers (A=156-160), utilizing the Interacting Boson Model-1 (IBM-1) within a broken SU(3) symmetry framework. Through this approach, we systematically calculated and analyzed the energy spectra, B(E2) transition probabilities, quadrupole moments, and potential energy surface (PES) which provided valuable insights into the shape and collective behavior of nuclei, as well as the decay properties of the selected Gd isotopes. The broken SU(3) symmetries provide a good description to the isotopes under study. This comprehensive analysis enhances the understanding of the nuclear structure …


Skin Microbiome: Current Target For Cosmeceuticals, Priyanka Kakkar, Neeraj Wadhwa 2024 Department of Biotechnology, Jaypee Institute of Information Technology, Noida, India

Skin Microbiome: Current Target For Cosmeceuticals, Priyanka Kakkar, Neeraj Wadhwa

Karbala International Journal of Modern Science

Skin acts as a barrier to the external environment and perform various functions like maintaining internal homeostasis, sensations to touch based stimuli, vitamin D production and defence against foreign pathogens, prevent dehydration. Skin has its own diverse microbiota like bacteria, virus, fungi that is collectively called as skin microbiome. Skin microbiome balance is disturbed (condition called dysbiosis) by both internal and external factors which lead to skin problems like acne, psoriasis, dandruff. It is important to maintain the healthy skin ecosystem. Cosmeceuticals i.e., combination of cosmetic and pharmaceuticals, is a recent trend in the skin care industry where we add …


Experimental Characterization, Computational Investigation, And Structure-Property–Activity Relationship Studies Of Nickel Ferrite Nanostructures, Ali Ben Ahmed 2024 University of Sfax, Faculty of Science of Sfax, Laboratory of Applied Physic, Sfax 3018 Tunisia

Experimental Characterization, Computational Investigation, And Structure-Property–Activity Relationship Studies Of Nickel Ferrite Nanostructures, Ali Ben Ahmed

Polytechnic Journal

Intending to predict the multifunctionality of Nickel ferrite in several technological and medical fields, we have prepared nickel ferrite nanostructure by coprecipitation method. X-ray Diffraction (XRD) is used to determine the crystalline structure and phase composition of materials by analyzing the pattern of X-rays scattered by the atoms within the material. Fourier Transform Infrared Spectroscopy (FTIR) provides information about a material's chemical bonds and functional groups by analyzing how it absorbs infrared light at various wavelengths. Scanning Electron Microscopy (SEM) offers high-resolution images of the material's surface morphology and texture by scanning it with a focused beam of electrons. Transmission …


Road Signs Detection Using Ssd Mobilenetv2, Zahraa Salah Dhaif, Nidhal K. El Abbadi 2024 Informatics Institute for Postgraduate Studies, Iraqi Commission for Computers and Informatics, Baghdad, Iraq

Road Signs Detection Using Ssd Mobilenetv2, Zahraa Salah Dhaif, Nidhal K. El Abbadi

Karbala International Journal of Modern Science

One of the most critical challenges for self-driving vehicles is accurately identifying traffic signs, which are essential for self-navigation and decision-making. Systems for the detection and recognition of road signs play a crucial role in this process by providing vital information for the vehicle's decision-making. This study proposes an approach for road sign identification and recognition utilising the TensorFlow Object Detection API and the SSD MobileNet V2 FPN Lite model.

In this proposal, we combine the efficiency and accuracy of SSD with the lightweight architecture of MobileNet to achieve excellent performance in object detection benchmarks while maintaining a small model …


An Introduction To The Time-Independent Schrödinger Equation And Methods To Solve It, Vu Giang, Alex Gnech 2024 Old Dominion University

An Introduction To The Time-Independent Schrödinger Equation And Methods To Solve It, Vu Giang, Alex Gnech

OUR Journal: ODU Undergraduate Research Journal

The Time-Independent Schrödinger Equation is a linear elliptic PDE that describes quantum-mechanical systems. Its significance in the science of submicroscopic phenomena, particularly quantum mechanics, is as central as Newton’s laws of motion are to classical mechanics. This study uses various methods, including novel neural networks and finite difference schemes, to solve the one-dimensional two-body equation.


Intelligrader: A Framework For Automatic Short Answer Grading, Inconsistency Check And Feedback In Educational Context - Conception, Implementation And Evaluation, Paradesi Sree Lakshmi, Jay B. Simha, Rajeev Ranjan 2024 School of Computer Science and Applications, REVA University, Bengaluru, India

Intelligrader: A Framework For Automatic Short Answer Grading, Inconsistency Check And Feedback In Educational Context - Conception, Implementation And Evaluation, Paradesi Sree Lakshmi, Jay B. Simha, Rajeev Ranjan

Karbala International Journal of Modern Science

Automatic Short Answer Grading (ASAG), an escalating realm in natural language understanding, constitutes a focal point of research within the broader field of learning analytics. Over time, many ASAG solutions have been proposed to address the difficulties in teaching. However, no work addressed three crucial aspects of evaluation together, i.e., i) automatic evaluation of brief subjective/descriptive answers written in English, ii) identifying the evaluation inconsistency, and iii) provision of providing feedback about inconsistent evaluation to the evaluator. The current work proposes IntelliGrader, a comprehensive ASAG system that addresses the above-mentioned issues. Automated grading is accomplished through a model answer-based approach. …


Isolation And Characterization Of Fermenting Bacterial Isolates From Vinegar Industry Waste In Local Markets Of Wasit Province, Tayseer Shamran Al-Deresawi 2024 Department of Biology, College of Education for Pure Sciences, University of Wasit, Al-Kut City, Iraq

Isolation And Characterization Of Fermenting Bacterial Isolates From Vinegar Industry Waste In Local Markets Of Wasit Province, Tayseer Shamran Al-Deresawi

Karbala International Journal of Modern Science

The use of waste in the vinegar industry is an important practice of the food industry worldwide; however, this critical practice is neglected in many parts of Iraq. According to this, the current study was conducted to isolate and characterize fermenting bacterial organisms from this waste in Wasit Province, Iraq. Samples of vinegar industry by-products were collected from local businesses. These samples were prepared by using Hestrin-Schramm (HS) medium. Two methods, direct and indirect inoculations, were followed. The purified growth was examined using morphological and biochemical tests. Moreover, PCR was employed to confirm the identity of each bacterial isolate. The …


Temperature-Dependent Quantum Beats Between Neutral And Charged Excitons In Monolayer Mose2, İBRAHİM SARPKAYA 2024 TÜBİTAK

Temperature-Dependent Quantum Beats Between Neutral And Charged Excitons In Monolayer Mose2, İbrahi̇m Sarpkaya

Turkish Journal of Physics

We studied the interaction between the neutral and charged excitons of monolayer MoSe2 at various temperatures via quantum beat spectroscopy in the time domain. We introduced temperature as an efficient control knob to regulate the relative photoluminescence intensities of the neutral and charged excitons to obtain maximum quantum beat resolution. Also, our quantum beat measurements under different temperatures indicate that the decoherence time of the coupled exciton-trion state slightly decreases from 530 fs at 3.5 K to 420 fs at 63 K with increased temperature due to the low-energy acoustic phonon-induced dephasing.


Alternative Scenarios For The Lhc Based Electron-Proton Collider, AHMET NURİ AKAY, BURAK DAĞLI, BORA KETENOĞLU, ARİF ÖZTÜRK, SALEH SULTANSOY 2024 TÜBİTAK

Alternative Scenarios For The Lhc Based Electron-Proton Collider, Ahmet Nuri̇ Akay, Burak Dağli, Bora Ketenoğlu, Ari̇f Öztürk, Saleh Sultansoy

Turkish Journal of Physics

Construction of the ERLC (twin LC) collider tangential to LHC will allow investigating ep collisions at essentially higher center-of-mass energies than ERL-50 and LHC based ep collider. Luminosity estimations show that values well exceeding 1034 cm−2s−1 can be achieved for ERLC and HL-LHC based ep colliders. Certainly, proposed ep colliders have great potential for clarifying QCD basics and new physics search in addition to providing precise PDFs for adequate interpretation of the LHC experimental data. Another alternative to the ERL-50 is to construct an e-ring with the same energy and length. In this case, luminosity of order 1034cm−2s−1 can be …


Exploring Black Hole Entropy, Spacetime Perturbations, And Their Applications In Astrophysics, Ashley Meglino 2024 University of North Florida

Exploring Black Hole Entropy, Spacetime Perturbations, And Their Applications In Astrophysics, Ashley Meglino

PANDION: The Osprey Journal of Research and Ideas

Abstract

Tidal deformations and quasinormal frequencies result when a black hole experiences a perturbation to its geometry, such as by a small mass or a field. These effects can be measured experimentally from gravitational wave data or calculated mathematically using various methods. This paper details various studies that were done to develop meaningful and accurate calculations of tidal Love numbers and quasinormal frequencies, as well as the motivations for such efforts. In addition, various attempts to formulate a more sound interpretation of black hole entropy are discussed, including the shortcomings of some and the significance of these efforts in other …


Optimal Reconstruction Of The Hellings And Downs Correlation, Bruce Allen, Joseph D. Romano 2024 The University of Texas Rio Grande Valley

Optimal Reconstruction Of The Hellings And Downs Correlation, Bruce Allen, Joseph D. Romano

Physics and Astronomy Faculty Publications and Presentations

Pulsar timing arrays (PTAs) detect gravitational waves (GWs) via the correlations they create in the arrival times of pulses from different pulsars. The mean correlation, a function of the angle between the directions to two pulsars, was predicted in 1983 by Hellings and Downs (HD). Observation of this angular pattern is crucial evidence that GWs are present, so PTAs ``reconstruct the HD curve'' by estimating the correlation using pulsar pairs separated by similar angles. Several studies have examined the amount by which this curve is expected to differ from the HD mean. The variance arises because (a) a finite set …


Computational And Experimental Data For Undoped And Er-Doped Lithium Tantalate Nanofluorescent Probes, Mkhitar A. Hobosyan, Andrea Pelayo Carvajal, Bhupendra B. Srivastava, Tamanna Zakia, Mohammed Jasim Uddin, Karen S. Martirosyan, Eric Rodriguez, Kofi Nketia Ackaah-Gyasi, Nicholas Dimakis 2024 The University of Texas Rio Grande Valley

Computational And Experimental Data For Undoped And Er-Doped Lithium Tantalate Nanofluorescent Probes, Mkhitar A. Hobosyan, Andrea Pelayo Carvajal, Bhupendra B. Srivastava, Tamanna Zakia, Mohammed Jasim Uddin, Karen S. Martirosyan, Eric Rodriguez, Kofi Nketia Ackaah-Gyasi, Nicholas Dimakis

Physics and Astronomy Faculty Publications and Presentations

The density functional theory (DFT) and experimental data presented in this paper refer to the research article “Computational and experimental study on undoped and Er-doped lithium tantalate nano fluorescent probes”. The DFT data contain electronic and optical properties for both LiTaO3 and LiTaO3:Er+3, with Er+3 occupying either Li or Ta sites at 4.167 mol. %. All these properties were calculated at the generalized gradient approximation (GGA) limit. Additionally, electronic information was calculated using the hybrid functional by Heyd, Scuseria, and Ernzerho (HSE06), which accurately predicts the location in energy for all Er-4f orbitals. We also include simulated X-ray near edge …


First-Principles Calculations Of Thermoelectric Properties Of Fe-Based Full- Heusler Fe2cusi, Ai Nurlaela, Dwi Nanto, Anugrah Azhar, Elvan Yuniarti, Tony Kristiantoro, Dedi Dedi 2024 Physic Education Departement, Syarif Hidayatullah State Islamic University Jakarta, Jl. Ir H. Juanda No.95, Cempaka Putih, Banten, 15412, Indonesia

First-Principles Calculations Of Thermoelectric Properties Of Fe-Based Full- Heusler Fe2cusi, Ai Nurlaela, Dwi Nanto, Anugrah Azhar, Elvan Yuniarti, Tony Kristiantoro, Dedi Dedi

Makara Journal of Science

A first-principle study using density functional theory (DFT) and Boltzmann transport was conducted to evaluate the thermoelectric (TE) properties of an Fe-based full-Heusler alloy. The compound studied is Fe2CuSi with a Cu2MnAl-type structure. The electronic properties of Fe2CuSi were obtained using DFT calculations by running the Quantum ESPRESSO (QE) package. By contrast, TE properties, including electron thermal conductivity, electric conductivity, and Seebeck coefficient, were computed using a semi-empirical Boltzmann transport model solved through the BoltzTraP software at 50–1,500 K temperature range. The spin-orbit coupling effect on these properties was also evaluated, demonstrating notable effects …


Optimal Radar Ranging Pulse To Resolve Two Reflectors, Andrew N. Jordan, John C. Howell, Achim Kempf, Shunxing Zhang, Derek White 2024 Chapman University

Optimal Radar Ranging Pulse To Resolve Two Reflectors, Andrew N. Jordan, John C. Howell, Achim Kempf, Shunxing Zhang, Derek White

Mathematics, Physics, and Computer Science Faculty Articles and Research

Previous work established fundamental bounds on subwavelength resolution for the radar range resolution problem, called superradar [Phys. Rev. Appl. 20, 064046 (2023)]. In this work, we identify the optimal waveforms for distinguishing the range resolution between two reflectors of identical strength, leveraging results in quantum metrology. We discuss both the unnormalized optimal waveform as well as the best square-integrable pulse and their variants. Using orthogonal function theory, we give an explicit algorithm to optimize the wave pulse in finite time to have the best performance. We also explore range resolution estimation with unnormalized waveforms with multiparameter methods to …


Settling Of Two Rigidly Connected Spheres, Z. Maches, Morgane Houssais 2024 University of California, Santa Barbara

Settling Of Two Rigidly Connected Spheres, Z. Maches, Morgane Houssais

Physics

Laboratory experiments and particle-resolved simulations are employed to investigate the settling dynamics of a pair of rigidly connected spherical particles of unequal size. They yield a detailed picture of the transient evolution and the terminal values of the aggregate's orientation angle and its settling and drift velocities as functions of the aspect ratio and the Galileo number, which denotes the ratio of buoyancy and viscous forces acting on the aggregate. At low to moderate values of, the aggregate's orientation and velocity converge to their terminal values monotonically, whereas for higher -values the aggregate tends to undergo a more complex motion. …


China Spallation Neutron Source And Southern Advance Light Source, Hesheng CHEN 2024 Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, China

China Spallation Neutron Source And Southern Advance Light Source, Hesheng Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

China Spallation Neutron Source provides a large multidisciplinary platform for advanced neutron scattering research and application for cutting-edge research in basic science and many fields of the national demands. Its comprehensive performance is in the international advanced level, and has significantly improved the scientific and technological capability and innovation abilities in related fields. The successful construction of China Spallation Neutron Source has greatly promoted the development of the national large science and technology infrastructure in the Guangdong-Hong Kong-Macao Greater Bay Area, and provides important support to the comprehensive national science center in the Greater Bay Area. The synchrotron radiation light …


Synthesis Of Zno: Zro2 Nanocomposites Using Green Method For Medical Applications, Mohammed J. Tuama, Maysoon F. Alias 2024 Physics Department, College of Science, University of Baghdad, Jadriya, Baghdad, Iraq

Synthesis Of Zno: Zro2 Nanocomposites Using Green Method For Medical Applications, Mohammed J. Tuama, Maysoon F. Alias

Karbala International Journal of Modern Science

These days, nanocomposites are very popular, especially in medical applications. The spread of diseases in general, and those caused by microbes and cancerous diseases in particular, and the increased resistance of these diseases to antibiotics, have led to the need for the rapid, low-cost, and environmentally friendly production of nanocomposites. To create the chemical G-ZnO: ZrO2 and S-ZnO: ZrO2 (green technique), two different plant extracts were utilized: Z. officinal and S. aromaticum. The effective synthesis and acceptable properties features of the nanoparticles were confirmed using characterization techniques such as X-ray diffraction (XRD), Fourier transform infrared (FTIR) , diffuse reflectance spectroscopy …


Search For Core Collapse Supernovae Signals In Ligo’S Third Observation Run Using A Network Of Gravitational Wave Detectors Integrated With A Multiclass Convolutional Neural Network, Shahrear Khan Faisal, Gaukhar Nurbek, Michael Benjamin, Bhawana Sedhai, Soma Mukherjee 2024 The University of Texas Rio Grande Valley

Search For Core Collapse Supernovae Signals In Ligo’S Third Observation Run Using A Network Of Gravitational Wave Detectors Integrated With A Multiclass Convolutional Neural Network, Shahrear Khan Faisal, Gaukhar Nurbek, Michael Benjamin, Bhawana Sedhai, Soma Mukherjee

Physics and Astronomy Faculty Publications and Presentations

In the existing body of literature, numerous waveforms of core collapse supernovae (CCSN) have emerged from extensive simulations conducted in high-performance computing facilities globally. These waveforms exhibit distinct characteristics related to their explosion mechanisms, influenced by parameters such as progenitor mass, angular momentum, gravitational wave energy, peak frequency, duration, and equation of state. Core collapse supernovae stand out as highly anticipated sources in LIGO’s fourth observation (O4) run, prompting dedicated efforts to detect them. The integration of machine learning, specifically convolutional neural networks (CNN), has become a pivotal avenue for analysis. This study addresses a fundamental query: how can a …


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