Catherine O’Hara has a confession: She has no wisdom to impart. During the nearly seven decades she’s been alive, “I’ve learned nothing,” the Beetlejuice and Home Alone actress deadpans. That’s not true, but the comedian, 69, is prone to self-deprecating humor. It almost seems to be a reflex. When this People reporter tells her we’ll be discussing the events of her life, the two-time Emmy winner, who costars in the new movie Argylle, quips, “I’m so sorry.”