(Q90376489)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

title

Oridonin prevents insulin resistance-mediated cognitive disorder through PTEN/Akt pathway and autophagy in minimal hepatic encephalopathy (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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hepatic encephalopathy

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Weishan Zhuge

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Jian Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Xiaoai Lu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Ruimin You

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Leping Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Qichuan Zhuge

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

Saidan Ding

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

publication date

30 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular and Molecular Medicine

13 April 2020

published in

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13 April 2020

volume

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13 April 2020

issue

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13 April 2020

page(s)

61-78

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

Mechanism of insulin resistance associated with liver cirrhosis

13 April 2020

cites work

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12 December 2020

Glucose metabolism in cirrhosis: a review with some perspectives for the future

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12 December 2020

A study of carbohydrate metabolism in postnecrotic cirrhosis liver

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12 December 2020

Glucose tolerance, free fatty acid, and serum insulin responses in patients with cirrhosis

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12 December 2020

Glucose intolerance and insulin resistance in patients with liver disease. II. A study of etiologic factors and evaluation of insulin actions

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12 December 2020

Carbohydrate metabolism studies in cirrhosis of the liver

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12 December 2020

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells

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12 December 2020

The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes

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12 December 2020

Minimal hepatic encephalopathy impairs fitness to drive

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12 December 2020

Muscle-specific Pten deletion protects against insulin resistance and diabetes

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12 December 2020

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

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12 December 2020

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

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12 December 2020

Implanted cannula-mediated repetitive administration of Abeta25-35 into the mouse cerebral ventricle effectively impairs spatial working memory

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12 December 2020

New twist on neuronal insulin receptor signaling in health, disease, and therapeutics

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12 December 2020

Peroxisome proliferator-activated receptor gamma as a drug target in the pathogenesis of insulin resistance

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12 December 2020

Regulation of membrane traffic by phosphoinositide 3-kinases

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12 December 2020

Loss of autophagy in the central nervous system causes neurodegeneration in mice

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12 December 2020

Pten regulates neuronal arborization and social interaction in mice

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12 December 2020

The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease

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12 December 2020

Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment

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12 December 2020

Studies on the cell-immunosuppressive mechanism of Oridonin from Isodon serra.

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12 December 2020

Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation

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12 December 2020

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats.

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12 December 2020

Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease

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12 December 2020

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

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12 December 2020

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

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12 December 2020

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

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12 December 2020

Multiple-modulation effects of Oridonin on the production of proinflammatory cytokines and neurotrophic factors in LPS-activated microglia

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12 December 2020

Minimal hepatic encephalopathy.

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12 December 2020

Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance

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12 December 2020

The ginsenoside Rg3 has a stimulatory effect on insulin signaling in L6 myotubes.

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12 December 2020

Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration

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12 December 2020

Current and future diagnosis of hepatic encephalopathy

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12 December 2020

Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons

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12 December 2020

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

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12 December 2020

How does diabetes accelerate Alzheimer disease pathology?

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12 December 2020

Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis.

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12 December 2020

Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone.

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12 December 2020

PPARγ agonist improves neuronal insulin receptor function in hippocampus and brain mitochondria function in rats with insulin resistance induced by long term high-fat diets

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12 December 2020

Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals

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12 December 2020

Terpenoids as potential anti-Alzheimer's disease therapeutics.

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12 December 2020

The functions and regulation of the PTEN tumour suppressor

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12 December 2020

PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance

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12 December 2020

Effects of metformin on learning and memory behaviors and brain mitochondrial functions in high fat diet induced insulin resistant rats.

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12 December 2020

DPP4-inhibitor improves neuronal insulin receptor function, brain mitochondrial function and cognitive function in rats with insulin resistance induced by high-fat diet consumption.

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12 December 2020

DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

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12 December 2020

Spatial memory impairment and changes in hippocampal morphology are triggered by high-fat diets in adolescent mice. Is there a role of leptin?

1 reference

12 December 2020

Inter-relationships among diet, obesity and hippocampal-dependent cognitive function.

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12 December 2020

Oridonin ameliorates neuropathological changes and behavioural deficits in a mouse model of cerebral amyloidosis

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12 December 2020

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

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12 December 2020

Intranasal insulin therapy for cognitive impairment and neurodegeneration: current state of the art

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12 December 2020

β-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice

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12 December 2020

Oridonin inhibits hepatic stellate cell proliferation and fibrogenesis

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12 December 2020

Involvement of the AMPK-PTEN pathway in insulin resistance induced by high glucose in cultured rat podocytes.

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12 December 2020

Ginsenosides attenuate methylglyoxal-induced impairment of insulin signaling and subsequent apoptosis in primary astrocytes.

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12 December 2020

Brain changes underlying cognitive dysfunction in diabetes: what can we learn from MRI?

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12 December 2020

Oridonin attenuates Aβ1-42-induced neuroinflammation and inhibits NF-κB pathway

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12 December 2020

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models

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12 December 2020

Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive

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12 December 2020

Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes

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12 December 2020

Minimal hepatic encephalopathy impairs quality of life.

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12 December 2020

Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions

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12 December 2020

MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway

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12 December 2020

Capillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain Tissue

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12 December 2020

Oridonin Attenuates Synaptic Loss and Cognitive Deficits in an Aβ1-42-Induced Mouse Model of Alzheimer's Disease

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12 December 2020

Autophagy activation involved in hypoxic-ischemic brain injury induces cognitive and memory impairment in neonatal rats

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12 December 2020

Brain Development and Akt Signaling: the Crossroads of Signaling Pathway and Neurodevelopmental Diseases

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12 December 2020

Evaluation of prepulse inhibition and memory impairments at early stage of cirrhosis may be considered as a diagnostic index for minimal hepatic encephalopathy.

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12 December 2020

Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidative stress and endoplasmic reticulum stress

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12 December 2020

Insulin Resistance Disrupts the Interaction Between AKT and the NMDA Receptor and the Inactivation of the CaMKIV/CREB Pathway in Minimal Hepatic Encephalopathy

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12 December 2020

Insulin resistance among obese middle-aged is associated with decreased cerebrovascular reactivity.

1 reference

12 December 2020

Antenatal Treatment with Intravenous Immunoglobulin to Prevent Gestational Alloimmune Liver Disease: Comparative Effectiveness of 14-Week versus 18-Week Initiation.

1 reference

12 December 2020

Dopamine Burden Induced the Inactivation of Sonic Hedgehog Signaling to Cognitive Decline in Minimal Hepatic Encephalopathy

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12 December 2020

Oridonin protects against the inflammatory response in diabetic nephropathy by inhibiting the TLR4/p38-MAPK and TLR4/NF-κB signaling pathways

1 reference

12 December 2020

Ginsenoside Rg1 inhibits dietary-induced obesity and improves obesity-related glucose metabolic disorders.

1 reference

12 December 2020

Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway.

1 reference

12 December 2020

Identifiers

DOI

10.1111/JCMM.14546

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

31568638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31568638%20AND%20SRC:MED&resulttype=core&format=json