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Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells
scientific article published on 24 June 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
title
Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
main subject
marginal zone B-cell
1 reference
based on heuristic
inferred from title
author name string
Sandrine Benhamron
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Boaz Tirosh
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
publication date
24 June 2011
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
published in
European Journal of Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
volume
41
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
page(s)
2390-2396
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
cites work
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Common corruption of the mTOR signaling network in human tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mTOR regulates memory CD8 T-cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Foxo1 regulates marginal zone B-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3 kinase signals BCR-dependent mature B cell survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TSC-mTOR signaling pathway regulates the innate inflammatory response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.201041336
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EJI.201041336
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
PubMed publication ID
21674478
1 reference
stated in
Europe PubMed Central
PubMed publication ID
21674478
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21674478%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
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