(Q84115558)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

J Duque-Afonso

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

A Yalcin

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

M Abdelkarim

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

M Lübbert

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

publication date

16 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

3062-3072

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21577204%20AND%20SRC:MED&resulttype=core&format=json

Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

1 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

High-resolution profiling of histone methylations in the human genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Williams-Beuren syndrome critical region-5/non-T-cell activation linker: a novel target gene of AML1/ETO.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

AML1/MTG8 oncogene suppression by small interfering RNAs supports myeloid differentiation of t(8;21)-positive leukemic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

LAB: a new membrane-associated adaptor molecule in B cell activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

MLL translocations, histone modifications and leukaemia stem-cell development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Gene silencing of the p15/INK4B cell-cycle inhibitor by hypermethylation: an early or later epigenetic alteration in myelodysplastic syndromes?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

The p21Waf1 pathway is involved in blocking leukemogenesis by the t(8;21) fusion protein AML1-ETO.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Williams-Beuren syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32

Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.32