(Q77420459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

K Y Tsai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Y Hu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

K F Macleod

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

D Crowley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

L Yamasaki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

T Jacks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

publication date

1 September 1998

1 reference

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5 December 2019

1 reference

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5 December 2019

volume

1 reference

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5 December 2019

issue

1 reference

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5 December 2019

page(s)

293-304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A.

5 December 2019

cites work

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7 January 2021

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

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7 January 2021

The retinoblastoma protein pathway in cell cycle control and cancer

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7 January 2021

E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

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7 January 2021

The E2F transcription factor is a cellular target for the RB protein

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7 January 2021

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

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7 January 2021

The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein

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7 January 2021

Requirement for a functional Rb-1 gene in murine development

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7 January 2021

Expression patterns of the E2F family of transcription factors during mouse nervous system development

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7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

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7 January 2021

E1A signaling to p53 involves the p19(ARF) tumor suppressor

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7 January 2021

Ras signalling and apoptosis

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7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

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7 January 2021

Human Cancer Syndromes: Clues to the Origin and Nature of Cancer

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7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

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7 January 2021

E2F-4, a new member of the E2F transcription factor family, interacts with p107

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7 January 2021

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

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7 January 2021

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

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7 January 2021

E2F-5, a new E2F family member that interacts with p130 in vivo

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7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

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7 January 2021

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation

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7 January 2021

Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

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7 January 2021

Effects of an Rb mutation in the mouse

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7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

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7 January 2021

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1 reference

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7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

1 reference

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7 January 2021

The embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor

1 reference

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7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

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7 January 2021

Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation

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7 January 2021

Targeted disruption of p107: functional overlap between p107 and Rb

1 reference

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7 January 2021

The retinoblastoma protein binds to a family of E2F transcription factors

1 reference

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7 January 2021

bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

1 reference

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7 January 2021

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

1 reference

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

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7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

1 reference

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7 January 2021

An E2F-like repressor of transcription

1 reference

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7 January 2021

The retinoblastoma gene family: cousins with overlapping interests

1 reference

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7 January 2021

Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

1 reference

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7 January 2021

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors

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7 January 2021

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

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7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

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7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

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7 January 2021

E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

1 reference

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7 January 2021

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

1 reference

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7 January 2021

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

1 reference

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7 January 2021

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

1 reference

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7 January 2021

Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

1 reference

7 January 2021

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980274-9

7 January 2021

10.1016/S1097-2765(00)80274-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9774968%20AND%20SRC:MED&resulttype=core&format=json