(Q59125485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

title

A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Yijin Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Alasdair Dj Freeman

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

David M J Lilley

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

language of work or name

English

0 references

publication date

1 November 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

published in

Nucleic Acids Research

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24 April 2020

volume

1 reference

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24 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

page(s)

11089-11098

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

24 April 2020

start time

24 September 2018

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

The SMX DNA Repair Tri-nuclease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

GEN1 from a thermophilic fungus is functionally closely similar to non-eukaryotic junction-resolving enzymes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Regulatory control of the resolution of DNA recombination intermediates during meiosis and mitosis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1-Top3.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Mechanism of Holliday junction resolution by the human GEN1 protein

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

PHENIX: a comprehensive Python-based system for macromolecular structure solution

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Identification of Holliday junction resolvases from humans and yeast

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

New insight into the recognition of branched DNA structure by junction-resolving enzymes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Flap endonuclease 1: a central component of DNA metabolism

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Human exonuclease I is required for 5' and 3' mismatch repair

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Ensuring productive resolution by the junction-resolving enzyme RuvC: large enhancement of the second-strand cleavage rate

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Near-simultaneous DNA cleavage by the subunits of the junction-resolving enzyme T4 endonuclease VII.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Structures of bulged three-way DNA junctions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

The characterization of a mammalian DNA structure-specific endonuclease

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB). A nomenclature of junctions and branchpoints in nucleic acids. Recommendations 1994.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

The Bloom's syndrome gene product is homologous to RecQ helicases

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6237754

Facile cruciform formation by an (A-T)34 sequence from a Xenopus globin gene

30 November 2018

1 reference

12 December 2020

Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases

1 reference

12 December 2020

Yeast Resolving Enzyme CCE1 Makes Sequential Cleavages in DNA Junctions within the Lifetime of the Complex†

1 reference

12 December 2020

A conserved loop-wedge motif moderates reaction site search and recognition by FEN1

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKY863

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

30247722

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30247722%20AND%20SRC:MED&resulttype=core&format=json