(Q43867718)

27 November 2017

title

Influence of a dominant cryptic epitope on autoimmune T cell tolerance (English)

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27 November 2017

Stephen M Anderton

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27 November 2017

Nicholas J Viner

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27 November 2017

Philip Matharu

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27 November 2017

Pauline A Lowrey

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27 November 2017

David C Wraith

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27 November 2017

language of work or name

English

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publication date

14 January 2002

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27 November 2017

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27 November 2017

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27 November 2017

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27 November 2017

page(s)

175-181

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Capture and processing of exogenous antigens for presentation on MHC molecules.

27 November 2017

cites work

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Dominance and crypticity of T cell antigenic determinants

21 January 2018

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Characterization of a major encephalitogenic T cell epitope in SJL/J mice with synthetic oligopeptides of myelin basic protein

21 January 2018

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Selection of encephalitogenic rat T-lymphocyte clones recognizing an immunodominant epitope on myelin basic protein

21 January 2018

1 reference

Two minor determinants of myelin basic protein induce experimental allergic encephalomyelitis in SJL/J mice

21 January 2018

1 reference

T cell determinants of myelin basic protein include a unique encephalitogenic I-E-restricted epitope for Lewis rats.

21 January 2018

1 reference

Immunological aspects of experimental allergic encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy.

21 January 2018

1 reference

Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production

21 January 2018

1 reference

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

21 January 2018

1 reference

Appreciating the complexity of MHC class II peptide binding: lysozyme peptide and I-Ak

21 January 2018

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T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis

21 January 2018

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Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein

21 January 2018

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Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients

21 January 2018

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Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain

21 January 2018

1 reference

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro

21 January 2018

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Phenotypic characterization of five dendritic cell subsets in human tonsils

21 January 2018

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Tolerance, danger, and the extended family

21 January 2018

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Kinetics of peptide uptake and tissue distribution following a single intranasal dose of peptide

21 January 2018

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Modulation of the immunogenicity of antigenic determinants by their flanking residues

21 January 2018

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Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.

21 January 2018

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The nature of cryptic epitopes within the self-antigen myelin basic protein

21 January 2018

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A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease

21 January 2018

1 reference

Adoptive transfer of experimental allergic encephalomyelitis and localization of the encephalitogenic epitope in the SWR mouse

21 January 2018

1 reference

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

21 January 2018

1 reference

Control of antigen presentation by a single protease cleavage site

21 January 2018

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Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

21 January 2018

1 reference

Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes

21 January 2018

1 reference

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

21 January 2018

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Characterization of a Recombinant Murine 18.5-kDa Myelin Basic Protein

21 January 2018

1 reference

T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis

21 January 2018

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T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

21 January 2018

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Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

21 January 2018

1 reference

7 January 2021

Affinity for class II MHC determines the extent to which soluble peptides tolerize autoreactive T cells in naive and primed adult mice--implications for autoimmunity

1 reference

7 January 2021

Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin

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7 January 2021

Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms

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7 January 2021

Therapeutic potential of TCR antagonists is determined by their ability to modulate a diverse repertoire of autoreactive T cells

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7 January 2021

A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor

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7 January 2021

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

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7 January 2021

Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype

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7 January 2021

Variable synthesis and expression of E alpha and Ae (E beta) Ia polypeptide chains in mice of different H-2 haplotypes

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7 January 2021

Identifiers

DOI

10.1038/NI756

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27 November 2017

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