(Q43036301)

12 November 2017

title

Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection (English)

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12 November 2017

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12 November 2017

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12 November 2017

Amalia Penna

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12 November 2017

Alessandra Orlandini

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12 November 2017

Massimo Pilli

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12 November 2017

Alessandro Zerbini

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12 November 2017

Luca Sacchelli

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12 November 2017

Sergio Mezzadri

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12 November 2017

language of work or name

English

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publication date

1 March 2007

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12 November 2017

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12 November 2017

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12 November 2017

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12 November 2017

page(s)

588-601

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The impairment of CD8 responses limits the selection of escape mutations in acute hepatitis C virus infection

12 November 2017

cites work

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Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection

21 January 2018

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Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection

21 January 2018

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Immunology of hepatitis B virus and hepatitis C virus infection

21 January 2018

1 reference

7 January 2021

Stealth and cunning: hepatitis B and hepatitis C viruses

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7 January 2021

Restoring function in exhausted CD8 T cells during chronic viral infection

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7 January 2021

The B7-CD28 superfamily

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7 January 2021

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

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7 January 2021

Los Alamos Hepatitis C Immunology Database

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7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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7 January 2021

Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response

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7 January 2021

Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

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7 January 2021

Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen

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7 January 2021

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

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7 January 2021

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

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7 January 2021

Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection

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7 January 2021

Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C.

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7 January 2021

Subversion of effector CD8+ T cell differentiation in acute hepatitis C virus infection: exploring the immunological mechanisms

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7 January 2021

Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

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7 January 2021

Cellular immune responses in seronegative sexual contacts of acute hepatitis C patients

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7 January 2021

Analysis of successful immune responses in persons infected with hepatitis C virus

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7 January 2021

Effects of antiviral therapy on the cellular immune response in acute hepatitis C.

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7 January 2021

Immune evasion versus recovery after acute hepatitis C virus infection from a shared source

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7 January 2021

Determinants of viral clearance and persistence during acute hepatitis C virus infection

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7 January 2021

Heterologous T cell immunity in severe hepatitis C virus infection

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7 January 2021

PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

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7 January 2021

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

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7 January 2021

Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers

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7 January 2021

Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection

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7 January 2021

Kinetics of the immune response during HBV and HCV infection.

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7 January 2021

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

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7 January 2021

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus

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7 January 2021

Cellular immune selection with hepatitis C virus persistence in humans

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7 January 2021

CD8 Epitope Escape and Reversion in Acute HCV Infection

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7 January 2021

Divergent and convergent evolution after a common-source outbreak of hepatitis C virus

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7 January 2021

Cytotoxic T lymphocytes: all roads lead to death

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7 January 2021

Lymphocyte-mediated cytotoxicity.

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7 January 2021

Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia

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7 January 2021

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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7 January 2021

Most antiviral CD8 T cells during chronic viral infection do not express high levels of perforin and are not directly cytotoxic

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7 January 2021

Viral immune evasion due to persistence of activated T cells without effector function

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7 January 2021

Antiviral CD8+ T cell responses in neonatal mice: susceptibility to polyoma virus-induced tumors is associated with lack of cytotoxic function by viral antigen-specific T cells

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7 January 2021

Simian immunodeficiency virus (SIV) infection of a rhesus macaque induces SIV-specific CD8(+) T cells with a defect in effector function that is reversible on extended interleukin-2 incubation

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7 January 2021

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

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7 January 2021

Plasticity of T cell memory responses to viruses

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7 January 2021

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7 January 2021

PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

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7 January 2021

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

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7 January 2021

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

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7 January 2021

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation

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7 January 2021

Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection.

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7 January 2021

Identifiers

DOI

10.1002/HEP.21541

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12 November 2017

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