(Q41544852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

title

A methotrexate-resistant human breast cancer cell line with multiple defects, including diminished formation of methotrexate polyglutamates (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

1 reference

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

28 August 2023

1 reference

K. H. Cowan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6206061

28 August 2023

J. Jolivet

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6206061

28 August 2023

language of work or name

English

0 references

publication date

1 September 1984

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

10 September 1984

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=6206061

full work available at URL

28 August 2023

http://intl.jbc.org/cgi/content/abstract/259/17/10793

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6206061

https://api.elsevier.com/content/article/PII:S002192581890582X?httpAccept=text/xml

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

https://api.elsevier.com/content/article/PII:S002192581890582X?httpAccept=text/plain

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Journal of Biological Chemistry

28 August 2023

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

volume

259

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

page(s)

10793-10800

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json

Isolation and partial characterization of three methotrexate-resistant phenotypes from Chinese hamster ovary cells

28 October 2019

cites work

1 reference

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Detective transport of amethopterin (methotrexate) as a mechanism of resistance to the antimetabolite in L5178Y leukemic cells

28 August 2023

1 reference

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28 August 2023

Sirotnak

1968

1 reference

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Sites of action of amethopterin: intrinsic and acquired drug resistance

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Purification and properties of dihydrofolate reductase from methotrexate-sensitive and methotrexate-resistant Chinese hamster ovary cells

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Methotrexate-resistant Chinese hamster ovary cells contain a dihydrofolate reductase with an altered affinity for methotrexate

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Acquired methotrexate resistance in lymphoblasts resulting from altered kinetic properties of dihydrofoltate reductase

28 August 2023

1 reference

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28 August 2023

1539

Albrecht

1972

1 reference

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Increased levels of folic acid reductase as a mechanism of resistance to amethopterin in leukemic cells.

28 August 2023

1 reference

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Hybridization of hamster cells with high and low folate reductase activity

28 August 2023

1 reference

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Amethopterin-induced changes in the multiple forms of dihydrofolate reductase from L1210 cells

28 August 2023

1 reference

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The development of resistance to methotrexate in a mouse melanoma cell line. I. Characterisation of the dihydrofolate reductases and chromosomes in sensitive and resistant cells

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Multiple forms of human dihydrofolate reductase messenger RNA. Cloning and expression in Escherichia coli of their DNA coding sequence

28 August 2023

1 reference

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28 August 2023

231

Domin

1981

1 reference

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Polygammaglutamyl metabolites of methotrexate.

28 August 2023

1 reference

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28 August 2023

408

Whitehead

1977

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28 August 2023

2585

Whitehead

1975

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28 August 2023

210

Rosenblatt

1978

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28 August 2023

2914

Gerwirtz

1979

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28 August 2023

4441

Poser

1981

1 reference

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Methotrexate polyglutamate synthesis by cultured human breast cancer cells

28 August 2023

1 reference

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Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

28 August 2023

1 reference

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28 August 2023

3352

Engel

1979

1 reference

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Influence of oxygen and culture media on plating efficiency of some mammalian tissue cells

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Competitive protein binding assay for methotrexate

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Protein measurement with the Folin phenol reagent

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

An Isotopic Assay for Thymidylate Synthetase*

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Characteristics of membrane transport of methotrexate by cultured human breast cancer cells

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Cleavage of naturally occurring folates to unsubstituted p-aminobenzoylpoly-γ-glutamates

28 August 2023

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)90582-X

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity

28 August 2023

1 reference

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28 August 2023

1497

Ayusawa

1981

1 reference

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28 August 2023

723

Washtien

1982

1 reference

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28 August 2023

287

White

1975

1 reference

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Studies with a mathematical model of folate metabolism

28 August 2023

1 reference

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28 August 2023

711

White

1976

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28 August 2023

2442

Chello

1976

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28 August 2023

478

Domin

1982

1 reference

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Isolation and biochemical characterization of folate deficient mutants of chinese hamster cells

28 August 2023

1 reference

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Folate-dependent enzymes in cultured Chinese hamster cells: Folylpolyglutamate synthetase and its absence in mutants auxotrophic for glycine + adenosine + thymidine

28 August 2023

1 reference

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2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline (tmq), a potent non-classical folate antagonist inhibitor--I effect on dihydrofolate reductase and growth of rodent tumors in vitro and in vivo

28 August 2023

1 reference

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28 August 2023

1655

Ohnoshi

1982

1 reference

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Regulation of methotrexate polyglutamate accumulation in vitro: effects of cellular folate content

28 August 2023

1 reference

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Changes in the chain length of folylpolyglutamates during liver regeneration

28 August 2023

1 reference

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28 August 2023

2751

Balinska

1981

1 reference

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28 August 2023

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6206061%20AND%20SRC:MED&resulttype=core&format=json