(Q39739616)

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Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells

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14 September 2017

Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells (English)

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14 September 2017

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neoplastic invasiveness

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L Xu

1

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14 September 2017

M B Nilsson

2

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14 September 2017

P Saintigny

3

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14 September 2017

T Cascone

4

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14 September 2017

M H Herynk

5

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14 September 2017

Z Du

6

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14 September 2017

P G Nikolinakos

7

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14 September 2017

Y Yang

8

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14 September 2017

L Prudkin

9

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14 September 2017

D Liu

10

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14 September 2017

J J Lee

11

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14 September 2017

F M Johnson

12

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14 September 2017

K-K Wong

13

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14 September 2017

L Girard

14

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14 September 2017

A F Gazdar

15

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14 September 2017

J D Minna

16

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14 September 2017

J M Kurie

17

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14 September 2017

I I Wistuba

18

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14 September 2017

J V Heymach

19

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14 September 2017

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15 February 2010

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14 September 2017

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14 September 2017

29

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14 September 2017

18

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14 September 2017

2616-2627

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Europe PubMed Central

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14 September 2017

EGFR antagonists in cancer treatment

1 reference

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14 September 2017

Signaling networks assembled by oncogenic EGFR and c-Met

1 reference

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

1 reference

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14 September 2017

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 reference

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14 September 2017

Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival

1 reference

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14 September 2017

Failure to prolyl hydroxylate hypoxia-inducible factor alpha phenocopies VHL inactivation in vivo

1 reference

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14 September 2017

Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression

1 reference

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14 September 2017

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

1 reference

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14 September 2017

Targeting the c-Met signaling pathway in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

1 reference

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14 September 2017

EGFR tyrosine kinase inhibitors decrease VEGF expression by both hypoxia-inducible factor (HIF)-1-independent and HIF-1-dependent mechanisms

1 reference

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14 September 2017

Interactions between hypoxia and epidermal growth factor receptor in non-small-cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

1 reference

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14 September 2017

Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)

1 reference

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14 September 2017

Differential expression of epidermal growth factor receptor, c-Met, and HER2/neu in chordoma compared with 17 other malignancies

1 reference

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14 September 2017

Erlotinib in previously treated non-small-cell lung cancer

1 reference

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14 September 2017

Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology

1 reference

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14 September 2017

Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions

1 reference

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14 September 2017

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data

1 reference

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14 September 2017

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

1 reference

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14 September 2017

Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors

1 reference

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14 September 2017

How to make tubes: signaling by the Met receptor tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected].

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

14 September 2017

Classification, staging and prognosis of lung cancer

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14 September 2017

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

1 reference

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14 September 2017

Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application

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14 September 2017

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

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14 September 2017

In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor

1 reference

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14 September 2017

Paracrine effects of hepatocyte growth factor/scatter factor on non-small-cell lung carcinoma cell lines

1 reference

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14 September 2017

Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas.

1 reference

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14 September 2017

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

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1 reference

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Amplification and overexpression of the met gene in spontaneously transformed NIH3T3 mouse fibroblasts

1 reference

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Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors

1 reference

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A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras

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Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway

1 reference

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Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins

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Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis

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14 September 2017

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

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Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox

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Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival

1 reference

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25 September 2017

Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

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Expression of c-met/HGF receptor in human non-small cell lung carcinomas in vitro and in vivo and its prognostic significance.

1 reference

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c-Met activation in lung adenocarcinoma tissues: an immunohistochemical analysis.

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20 August 2018

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1 reference

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Inhibition of human non-small cell lung tumors by a c-Met antisense/U6 expression plasmid strategy

1 reference

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Cytokines regulate c-Met expression in cultured astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378055

20 August 2018

Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.16

31 March 2020

The clinical significance of hepatocyte growth factor for non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.16

31 March 2020

Identifiers

10.1038/ONC.2010.16

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Europe PubMed Central

PMC publication ID

14 September 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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