(Q38468310)

3 September 2017

title

Platensimycin is a selective FabF inhibitor with potent antibiotic properties (English)

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3 September 2017

Lynn L Silver

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José R Tormo

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Olga Genilloud

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Jun Wang

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3 September 2017

Stephen M Soisson

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3 September 2017

Katherine Young

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3 September 2017

Wesley Shoop

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3 September 2017

Srinivas Kodali

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3 September 2017

Andrew Galgoci

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3 September 2017

Ronald Painter

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3 September 2017

Gopalakrishnan Parthasarathy

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3 September 2017

Yui S Tang

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3 September 2017

Richard Cummings

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3 September 2017

Sookhee Ha

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3 September 2017

Karen Dorso

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3 September 2017

Mary Motyl

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3 September 2017

Hiranthi Jayasuriya

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3 September 2017

John Ondeyka

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3 September 2017

Kithsiri Herath

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3 September 2017

Chaowei Zhang

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3 September 2017

Lorraine Hernandez

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3 September 2017

John Allocco

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3 September 2017

Angela Basilio

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3 September 2017

Francisca Vicente

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3 September 2017

Fernando Pelaez

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3 September 2017

Lawrence Colwell

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3 September 2017

Sang Ho Lee

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3 September 2017

Bruce Michael

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3 September 2017

Thomas Felcetto

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3 September 2017

Charles Gill

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3 September 2017

Jeffery D Hermes

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3 September 2017

Ken Bartizal

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3 September 2017

John Barrett

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3 September 2017

Dennis Schmatz

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3 September 2017

Joseph W Becker

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3 September 2017

Doris Cully

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3 September 2017

Sheo B Singh

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3 September 2017

language of work or name

English

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publication date

1 May 2006

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3 September 2017

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3 September 2017

volume

441

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3 September 2017

issue

7091

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3 September 2017

page(s)

358-361

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Empirical antibacterial drug discovery--foundation in natural products

3 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Natural products--the future scaffolds for novel antibiotics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Structural and functional organization of the animal fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Beta-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Response of Bacillus subtilis to cerulenin and acquisition of resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Discovery of FabH/FabF inhibitors from natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

The Claisen condensation in biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

Pi-pi interactions: the geometry and energetics of phenylalanine-phenylalanine interactions in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

The interpretation of protein structures: Estimation of static accessibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

7 January 2021

Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

7 January 2021

Thiolactomycin, a new antibiotic. III. In vitro antibacterial activity.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

7 January 2021

Determination of selectivity and efficacy of fatty acid synthesis inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04784

7 January 2021

Identifiers

DOI

10.1038/NATURE04784

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3 September 2017

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