(Q38349408)

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Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts

scientific article published on October 24, 2003

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Europe PubMed Central

PubMed publication ID

2 September 2017

Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein1 in mouse embryo fibroblasts (English)

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10.1016/J.BBRC.2003.09.086

https://api.crossref.org/works/10.1016/J.BBRC.2003.09.086

20 March 2024

multiple drug resistance

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based on heuristic

inferred from title

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10.1016/J.BBRC.2003.09.086

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10.1016/J.BBRC.2003.09.086

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3

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Ken Itoh

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14550278

20 March 2024

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Asako Hayashi

1

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2 September 2017

Hiroshi Suzuki

2

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2 September 2017

Masayuki Yamamoto

4

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2 September 2017

Yuichi Sugiyama

5

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2 September 2017

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1 October 2003

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2 September 2017

24 October 2003

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National Center for Biotechnology Information

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14550278

20 March 2024

full work available at URL

https://api.elsevier.com/content/article/PII:S0006291X03018886?httpAccept=text/xml

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10.1016/J.BBRC.2003.09.086

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https://api.elsevier.com/content/article/PII:S0006291X03018886?httpAccept=text/plain

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10.1016/J.BBRC.2003.09.086

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Biochemical and Biophysical Research Communications

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Europe PubMed Central

PubMed publication ID

2 September 2017

310

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PubMed publication ID

2 September 2017

3

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2 September 2017

824-829

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2 September 2017

The GS-X Pump in Plant, Yeast, and Animal Cells: Structure, Function, and Gene Expression

1

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Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

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Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition

3

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Hepatic secretion of conjugated drugs and endogenous substances

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Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells

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Frequent coordinated overexpression of the MRP/GS-X pump and gamma-glutamylcysteine synthetase genes in human colorectal cancers

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Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress.

7

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

10

1 reference

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

11

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

12

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Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

13

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

15

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Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

16

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Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

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Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression

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ABCG2 transports sulfated conjugates of steroids and xenobiotics

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Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

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Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.

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Mammalian ABC transporters in health and disease

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Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

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Identifiers

10.1016/J.BBRC.2003.09.086

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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