(Q38311731)

2 September 2017

title

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras (English)

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2 September 2017

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2 September 2017

James O McNamara

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2 September 2017

Yong Wang

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2 September 2017

Kristi D Viles

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2 September 2017

Rachel E Rempel

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2 September 2017

Eli Gilboa

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2 September 2017

Bruce A Sullenger

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2 September 2017

Paloma H Giangrande

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2 September 2017

publication date

25 June 2006

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2 September 2017

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

1005-1015

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

2 September 2017

cites work

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer

21 January 2018

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Delivering RNA interference to the mammalian brain.

21 January 2018

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Therapeutic potential of retroviral RNAi vectors

21 January 2018

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Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA.

21 January 2018

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

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RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

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Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

21 January 2018

1 reference

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

21 January 2018

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Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo.

21 January 2018

1 reference

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma

21 January 2018

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Polo-like kinases (Plks) and cancer

21 January 2018

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Polo-like kinases and oncogenesis

21 January 2018

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Killing cancer cells by flipping the Bcl-2/Bax switch.

21 January 2018

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Aptamers against extracellular targets for in vivo applications

21 January 2018

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Aptamers: an emerging class of therapeutics

21 January 2018

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Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors

21 January 2018

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Characterization of Dicer-deficient murine embryonic stem cells.

21 January 2018

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

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Activation of the interferon system by short-interfering RNAs

21 January 2018

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

21 January 2018

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Fully 2'-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA.

21 January 2018

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In vivo activity of nuclease-resistant siRNAs

21 January 2018

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Selection of 2'-fluoro-modified RNA aptamers for alleviation of cocaine and MK-801 inhibition of the nicotinic acetylcholine receptor

21 January 2018

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Protamine and protamine reactions

21 January 2018

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Efficient synthesis of nucleic acids heavily modified with non-canonical ribose 2'-groups using a mutantT7 RNA polymerase (RNAP).

21 January 2018

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Effects of rate, volume, and dose of intratumoral infusion on virus dissemination in local gene delivery

21 January 2018

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Delivery of siRNA and siRNA expression constructs to adult mammals by hydrodynamic intravascular injection

21 January 2018

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7 January 2021

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

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7 January 2021

Silencing of polo-like kinase (Plk) 1 via siRNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer.

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7 January 2021

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

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7 January 2021

Quantitative analysis of intratumoral infusion of color molecules

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7 January 2021

Identifiers

DOI

10.1038/NBT1223

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2 September 2017

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