(Q37319381)

19 August 2017

1 reference

title

Viral evasion and subversion of pattern-recognition receptor signalling (English)

1 reference

19 August 2017

Leonie Unterholzner

0 references

Andrew G Bowie

0 references

1 December 2008

1 reference

Nature Reviews Immunology

19 August 2017

published in

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

19 August 2017

page(s)

911-922

1 reference

Approaching the asymptote? Evolution and revolution in immunology

19 August 2017

cites work

1 reference

Translational mini-review series on Toll-like receptors: recent advances in understanding the role of Toll-like receptors in anti-viral immunity

21 January 2018

1 reference

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

21 January 2018

1 reference

TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.

21 January 2018

1 reference

Association of TLR4 polymorphisms with symptomatic respiratory syncytial virus infection in high-risk infants and young children

21 January 2018

1 reference

Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain

21 January 2018

1 reference

Interferon-inducible antiviral effectors

21 January 2018

1 reference

A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

31 March 2020

1 reference

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

31 March 2020

1 reference

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

31 March 2020

1 reference

Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.

31 March 2020

1 reference

MDA5/RIG-I and virus recognition.

31 March 2020

1 reference

When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction

31 March 2020

1 reference

Immunopathology of highly virulent pathogens: insights from Ebola virus

31 March 2020

1 reference

Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

31 March 2020

1 reference

Genetic analysis of resistance to viral infection

31 March 2020

1 reference

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

31 March 2020

1 reference

A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

31 March 2020

1 reference

Viral interference with IL-1 and toll signaling

31 March 2020

1 reference

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

31 March 2020

1 reference

Does Toll-like receptor 3 play a biological role in virus infections?

31 March 2020

1 reference

TLR3 in antiviral immunity: key player or bystander?

31 March 2020

1 reference

Sensing of viral infection and activation of innate immunity by toll-like receptor 3

31 March 2020

1 reference

Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases

31 March 2020

1 reference

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

31 March 2020

1 reference

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

31 March 2020

1 reference

Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces a cytotoxic T-cell response via MyD88.

31 March 2020

1 reference

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

31 March 2020

1 reference

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

31 March 2020

1 reference

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

31 March 2020

1 reference

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

31 March 2020

1 reference

Evasion of innate immunity by vaccinia virus

31 March 2020

1 reference

Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

31 March 2020

1 reference

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling

31 March 2020

1 reference

Identification and characterization of a novel bacterial virulence factor that shares homology with mammalian Toll/interleukin-1 receptor family proteins

31 March 2020

1 reference

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins

31 March 2020

1 reference

Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines

31 March 2020

1 reference

The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

31 March 2020

1 reference

IRAK-2 participates in multiple toll-like receptor signaling pathways to NFkappaB via activation of TRAF6 ubiquitination

31 March 2020

1 reference

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

31 March 2020

1 reference

The HTLV-I p30 interferes with TLR4 signaling and modulates the release of pro- and anti-inflammatory cytokines from human macrophages.

31 March 2020

1 reference

West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

31 March 2020

1 reference

Hepatitis C virus NS5A: tales of a promiscuous protein

31 March 2020

1 reference

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

31 March 2020

1 reference

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

31 March 2020

1 reference

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

31 March 2020

1 reference

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

31 March 2020

1 reference

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

31 March 2020

1 reference

VISA is an adapter protein required for virus-triggered IFN-beta signaling

31 March 2020

1 reference

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

31 March 2020

1 reference

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

31 March 2020

1 reference

5'-Triphosphate RNA is the ligand for RIG-I

31 March 2020

1 reference

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

31 March 2020

1 reference

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

31 March 2020

1 reference

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

31 March 2020

1 reference

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

31 March 2020

1 reference

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

31 March 2020

1 reference

A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

31 March 2020

1 reference

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

31 March 2020

1 reference

Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus

31 March 2020

1 reference

A protein covalently linked to poliovirus genome RNA

31 March 2020

1 reference

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

31 March 2020

1 reference

The Ebola virus VP35 protein is a suppressor of RNA silencing

31 March 2020

1 reference

Fragments of the HIV-1 Tat protein specifically bind TAR RNA.

31 March 2020

1 reference

The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

31 March 2020

1 reference

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

31 March 2020

1 reference

MDA-5 is cleaved in poliovirus-infected cells

31 March 2020

1 reference

Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor

31 March 2020

1 reference

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

31 March 2020

1 reference

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage

31 March 2020

1 reference

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

31 March 2020

1 reference

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

31 March 2020

1 reference

Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

31 March 2020

1 reference

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

31 March 2020

1 reference

Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses

31 March 2020

1 reference

Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

31 March 2020

1 reference

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

31 March 2020

1 reference

Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.

31 March 2020

1 reference

The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responses

31 March 2020

1 reference

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

31 March 2020

1 reference

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

31 March 2020

1 reference

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

31 March 2020

1 reference

Select paramyxoviral V proteins inhibit IRF3 activation by acting as alternative substrates for inhibitor of kappaB kinase epsilon (IKKe)/TBK1.

31 March 2020

1 reference

HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators

31 March 2020

1 reference

Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi's sarcoma-associated herpesvirus viral IRF homolog vIRF3.

31 March 2020

1 reference

Binding of Kaposi's sarcoma-associated herpesvirus K-bZIP to interferon-responsive factor 3 elements modulates antiviral gene expression

31 March 2020

1 reference

Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction

31 March 2020

1 reference

The infected cell protein 0 encoded by bovine herpesvirus 1 (bICP0) induces degradation of interferon response factor 3 and, consequently, inhibits beta interferon promoter activity

31 March 2020

1 reference

HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation

31 March 2020

1 reference

Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal Degradation

31 March 2020

1 reference

Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7

31 March 2020

1 reference

Vaccinia virus E3 protein prevents the antiviral action of ISG15

31 March 2020

1 reference

Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses

31 March 2020

1 reference

Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

31 March 2020

1 reference

African swine fever virus IAP-like protein induces the activation of nuclear factor kappa B

31 March 2020

1 reference

Inhibition of IkappaB kinase by vaccinia virus virulence factor B14

31 March 2020

1 reference

Kaposi's sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation

31 March 2020

1 reference

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

31 March 2020

1 reference

Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

31 March 2020

1 reference

TLR3 increases disease morbidity and mortality from vaccinia infection

31 March 2020

1 reference

TLR3 deficiency in patients with herpes simplex encephalitis

31 March 2020

1 reference

Interleukin-10 determines viral clearance or persistence in vivo

31 March 2020

1 reference

Resolution of a chronic viral infection after interleukin-10 receptor blockade

31 March 2020

1 reference

Vaccinia virus protein A52R activates p38 mitogen-activated protein kinase and potentiates lipopolysaccharide-induced interleukin-10

31 March 2020

1 reference

Subversion of the innate immune system by a retrovirus

31 March 2020

1 reference

DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication

31 March 2020

1 reference

Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function

31 March 2020

1 reference

Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense

31 March 2020

1 reference

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

31 March 2020

1 reference

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

31 March 2020

1 reference

Hepatitis C virus NS5A protein interacts with 2',5'-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner

31 March 2020

1 reference

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

31 March 2020

1 reference

Binding of influenza A virus NS1 protein to dsRNA in vitro

31 March 2020

1 reference

The NY-1 hantavirus Gn cytoplasmic tail coprecipitates TRAF3 and inhibits cellular interferon responses by disrupting TBK1-TRAF3 complex formation

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18989317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18989317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18989317

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2436

1 reference

19 August 2017

1 reference