(Q37123974)

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Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

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Europe PubMed Central

PMC publication ID

18 August 2017

Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling (English)

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Europe PubMed Central

PMC publication ID

18 August 2017

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Yusuf A. Hannun

10

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Yusuf A Hannun

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Europe PubMed Central

PMC publication ID

18 August 2017

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Archana Mukhopadhyay

1

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Europe PubMed Central

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18 August 2017

Sahar A Saddoughi

2

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Europe PubMed Central

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18 August 2017

Pengfei Song

3

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Europe PubMed Central

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18 August 2017

Iyad Sultan

4

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Europe PubMed Central

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18 August 2017

Suriyan Ponnusamy

5

1 reference

Europe PubMed Central

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18 August 2017

Can E Senkal

6

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Europe PubMed Central

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18 August 2017

Christopher F Snook

7

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Europe PubMed Central

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18 August 2017

Hugh K Arnold

8

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Europe PubMed Central

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18 August 2017

Rosalie C Sears

9

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18 August 2017

Besim Ogretmen

11

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18 August 2017

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21 November 2008

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Europe PubMed Central

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18 August 2017

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Europe PubMed Central

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18 August 2017

23

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18 August 2017

3

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Europe PubMed Central

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18 August 2017

751-763

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Europe PubMed Central

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18 August 2017

Nuclear sphingolipids: metabolism and signaling

1 reference

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14 September 2017

A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins

1 reference

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14 September 2017

Principles of bioactive lipid signalling: lessons from sphingolipids

1 reference

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14 September 2017

PP2A regulates the pro-apoptotic activity of FOXO1.

1 reference

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14 September 2017

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

1 reference

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14 September 2017

Mechanisms of ceramide-mediated repression of the human telomerase reverse transcriptase promoter via deacetylation of Sp3 by histone deacetylase 1

1 reference

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Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity

1 reference

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Relationship between the structure of SET/TAF-I /INHAT and its histone chaperone activity

1 reference

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14 September 2017

Rac1-induced cell migration requires membrane recruitment of the nuclear oncogene SET

1 reference

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14 September 2017

Tailoring structure-function and targeting properties of ceramides by site-specific cationization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Sphingolipid-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Sphingolipids of the nucleus and their role in nuclear signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Biologically active sphingolipids in cancer pathogenesis and treatment

1 reference

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14 September 2017

Molecular machinery for non-vesicular trafficking of ceramide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

The structural requirements for ceramide activation of serine-threonine protein phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Cathepsin D targeted by acid sphingomyelinase-derived ceramide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Role of human longevity assurance gene 1 and C18-ceramide in chemotherapy-induced cell death in human head and neck squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

14 September 2017

Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo.

1 reference

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14 September 2017

The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

1 reference

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14 September 2017

Sp1/Sp3-dependent regulation of human telomerase reverse transcriptase promoter activity by the bioactive sphingolipid ceramide

1 reference

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14 September 2017

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

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14 September 2017

Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase

1 reference

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14 September 2017

Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

29 September 2017

Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

29 September 2017

Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

27 June 2018

I1PP2A and I2PP2A. Two potent protein phosphatase 2A-specific inhibitor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

27 June 2018

Ceramide activates heterotrimeric protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

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NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

1 reference

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Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

3 September 2018

A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2653988

3 September 2018

Ceramide regulation of nuclear protein import

1 reference

https://pubmed.ncbi.nlm.nih.gov/19028839

12 December 2020

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Identifiers

10.1096/FJ.08-120550

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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