(Q35090344)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670350%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats (English)

1 reference

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8 February 2020

1 reference

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8 February 2020

Ravichandran Ramasamy

1 reference

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8 February 2020

Ann Marie Schmidt

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8 February 2020

author name string

Kellie McCormick Hallam

1 reference

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8 February 2020

Qing Li

1 reference

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8 February 2020

Radha Ananthakrishnan

1 reference

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8 February 2020

Yu S Zou

1 reference

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8 February 2020

Srinivasan Vedantham

1 reference

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8 February 2020

Shi Fang Yan

1 reference

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8 February 2020

publication date

15 August 2010

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8 February 2020

1 reference

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8 February 2020

volume

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8 February 2020

issue

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8 February 2020

page(s)

776-784

1 reference

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Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Endothelial nitric oxide synthase, caveolae and the development of atherosclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Enhanced peroxynitrite formation is associated with vascular aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Effects of aging and hypertension on endothelium-dependent vascular relaxation in rat carotid artery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Endothelial modulation of vascular relaxation to nitrovasodilators in aging and hypertension.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

3-Deoxyglucosone, an intermediate product of the Maillard reaction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Impaired contraction and relaxation in aorta from streptozotocin-diabetic rats: role of polyol pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Gene transfer of extracellular superoxide dismutase protects against vascular dysfunction with aging

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Effects of aging and atherosclerosis on endothelial and vascular smooth muscle function in humans.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Mechanisms of aging-induced impairment of endothelium-dependent relaxation: role of tetrahydrobiopterin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Central role for aldose reductase pathway in myocardial ischemic injury

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Selected contribution: Effects of aging on cerebrovascular tone and [Ca2+]i

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Effects of eparlestat on plasma levels of advanced glycation end products in patients with type 2 diabetes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Impact of aging on substrate metabolism by the human heart

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Effects of aging on vasoconstrictor and mechanical properties of rat skeletal muscle arterioles

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Aldose reductase activation is a key component of myocardial response to ischemia

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131144

Determination of methylglyoxal as 2-methylquinoxaline by high-performance liquid chromatography and its application to biological samples

27 September 2018

1 reference

12 December 2020

Effect of age on rabbit aortic responses to relaxant endothelium-dependent and endothelium-independent agents

1 reference

12 December 2020

Potent, orally active aldose reductase inhibitors related to zopolrestat: surrogates for benzothiazole side chain

1 reference

12 December 2020

Effects of Aldose Reductase Inhibition on Responses of the Corpus Cavernosum and Mesenteric Vascular Bed of Diabetic Rats

1 reference

12 December 2020

Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients

1 reference

12 December 2020

Mitochondrial metabolism and substrate competition in the aging Fischer rat heart

1 reference

12 December 2020

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

1 reference

12 December 2020

Different mechanisms of endothelial dysfunction with aging and hypertension in rat aorta

1 reference

12 December 2020

Metabolism of fructose-3-phosphate in the diabetic rat lens

1 reference

12 December 2020

Changes in endothelium-dependent vascular responses associated with spontaneous hypertension and age in rats

1 reference

12 December 2020

Role of polyol pathway in nonenzymatic glycation

1 reference

12 December 2020

Aging impairs functional, metabolic and ionic recovery from ischemia-reperfusion and hypoxia-reoxygenation

1 reference

12 December 2020

10.1111/J.1474-9726.2010.00606.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670350%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670350%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20670350

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20670350%20AND%20SRC:MED&resulttype=core&format=json