(Q34862221)

4 August 2017

1 reference

title

The regulation of actin remodeling during T-cell-APC conjugate formation (English)

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4 August 2017

Judy L Cannon

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4 August 2017

Janis K Burkhardt

series ordinal

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4 August 2017

publication date

1 August 2002

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4 August 2017

published in

Immunological Reviews

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4 August 2017

volume

186

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4 August 2017

page(s)

90-99

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T cell receptor signaling precedes immunological synapse formation

4 August 2017

cites work

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Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

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Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions

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The immunological synapse: a molecular machine controlling T cell activation

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Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

21 January 2018

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Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation

21 January 2018

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The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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Avidity regulation of integrins: the driving force in leukocyte adhesion

21 January 2018

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Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1.

21 January 2018

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LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain

21 January 2018

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Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

21 January 2018

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Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential

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Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

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Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70.

21 January 2018

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The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling

21 January 2018

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CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.

21 January 2018

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Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

21 January 2018

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A molecular framework for two-step T cell signaling: Lck Src homology 3 mutations discriminate distinctly regulated lipid raft reorganization events

21 January 2018

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Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

21 January 2018

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F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts.

21 January 2018

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Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

21 January 2018

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A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

21 January 2018

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Small GTPases in lymphocyte biology: Rho proteins take center stage

21 January 2018

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Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast

21 January 2018

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

21 January 2018

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A role for Cdc42 in macrophage chemotaxis

21 January 2018

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Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

21 January 2018

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21 January 2018

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Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

21 January 2018

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

21 January 2018

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Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus

21 January 2018

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Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

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Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome

21 January 2018

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T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome

21 January 2018

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Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome

21 January 2018

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Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

21 January 2018

1 reference

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Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes

21 January 2018

1 reference

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Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

21 January 2018

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The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Rho-family GTPases require the Arp2/3 complex to stimulate actin polymerization in Acanthamoeba extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

A homochiral metal-organic porous material for enantioselective separation and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Surfing pathogens and the lessons learned for actin polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Vav1 controls integrin clustering and MHC/peptide-specific cell adhesion to antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

Plagiarism and Pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

7 January 2021

Separation of integrin-dependent adhesion from morphological changes based on differential PLC specificities

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

7 January 2021

Intrinsic dendritic cell abnormalities in Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

7 January 2021

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2002.18609.X

7 January 2021

10.1034/J.1600-065X.2002.18609.X

Identifiers

DOI

1 reference

4 August 2017

1 reference