(Q34756497)

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Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury

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Europe PubMed Central

PubMed publication ID

4 August 2017

Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

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R M Shayiq

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

D W Roberts

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

K Rothstein

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

J E Snawder

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

W Benson

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

X Ma

6

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Europe PubMed Central

PubMed publication ID

4 August 2017

M Black

7

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Europe PubMed Central

PubMed publication ID

4 August 2017

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1 February 1999

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Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

29

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Europe PubMed Central

PubMed publication ID

4 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

451-463

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Acetaminophen hepatotoxicity

1 reference

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Reactive metabolites of phenacetin and acetaminophen: a review

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Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage

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Association of acetaminophen hepatotoxicity with fasting and ethanol use.

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Severe acetaminophen toxicity in a patient receiving isoniazid

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Mechanism of inhibition of hepatic bioactivation of paracetamol by dimethyl sulfoxide

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Acetaminophen activation by human liver cytochromes P450IIE1 and P450IA2

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Cytochrome P450-dependent metabolism of acetaminophen in four human transgenic lymphoblastoid cell lines

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Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics

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Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen.

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Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4

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Zonation of acetaminophen metabolism and cytochrome P450 2E1-mediated toxicity studied in isolated periportal and perivenous hepatocytes

1 reference

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Analysis of acetaminophen metabolites in urine by high-performance liquid chromatography with UV and amperometric detection

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Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention

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Molecular mechanisms of the hepatotoxicity caused by acetaminophen

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Cytochrome P-450 distribution in rat liver and the effect of sodium phenobarbitone administration

1 reference

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Glutathione replenishment capacity is lower in isolated perivenous than in periportal hepatocytes

1 reference

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Drug metabolism by periportal and perivenous rat hepatocytes. Comparison of phase I and phase II reactions and their inducibility during culture

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Transcriptional control of CYP2E1 in the perivenous liver region and during starvation.

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Studies on the mechanism of paracetamol-induced protection against paracetamol hepatotoxicity

1 reference

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7 January 2021

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Serum enzyme activities and hepatic triglyceride levels in acute and subacute acetaminophen-treated rats

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Long-term administration of toxic doses of paracetamol (acetaminophen) to rats

1 reference

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Pharmacological studies on the in vivo cataractogenicity of acetaminophen in mice and rabbits*1

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Purification and characterization of a hepatic mitochondrial cytochrome P-450 active in aflatoxin B1 metabolism

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The induction and competitive inhibition of a high affinity microsomal nitrosodimethylamine demethylase by ethanol

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

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Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

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Comparison of proliferating cell nuclear antigen to tritiated thymidine as a marker of proliferating hepatocytes in rats

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Metabolic basis for high paracetamol dosage without hepatic injury: a case study

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Mechanism of paracetamol toxicity

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N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

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Species differences in the hepatotoxicity of paracetamol are due to differences in the rate of conversion to its cytotoxic metabolite.

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Therapeutic doses of codeine have no effect on acetaminophen clearance or metabolism

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Glutathione alterations in rat liver after acute and subacute oral administration of paracetamol

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Centrilobular expression of ethanol-inducible cytochrome P-450 (IIE1) in rat liver

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Zonation of cytochrome P450 isozyme expression and induction in rat liver

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Effect of pretreatment of rats with carbon tetrachloride on tolerance development

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Autoprotection: stimulated tissue repair permits recovery from injury

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Hepatic regenerative enzyme activity after pericentral and periportal lobular toxic injury

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Role of CYP2E1 in the hepatotoxicity of acetaminophen

1 reference

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Redox signalling by transcription factors NF-kappa B and AP-1 in lymphocytes.

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Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen

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10.1002/HEP.510290241

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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