(Q34661064)

3 August 2017

title

Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation (English)

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3 August 2017

Yoshinori Tsukumo

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3 August 2017

Akihiro Tomida

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3 August 2017

Osamu Kitahara

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3 August 2017

Yusuke Nakamura

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3 August 2017

Shinichi Asada

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3 August 2017

Kazutoshi Mori

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3 August 2017

Takashi Tsuruo

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3 August 2017

language of work or name

English

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publication date

8 August 2007

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Journal of Biological Chemistry

3 August 2017

published in

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3 August 2017

volume

282

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3 August 2017

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3 August 2017

page(s)

29264-29272

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The mammalian unfolded protein response

3 August 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M705038200

ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

21 January 2018

1 reference

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Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response

21 January 2018

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

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Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

21 January 2018

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

21 January 2018

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XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

21 January 2018

1 reference

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pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

21 January 2018

1 reference

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Molecular cloning of nucleobindin, a novel DNA-binding protein that contains both a signal peptide and a leucine zipper structure

21 January 2018

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Isolation, characterization, and primary structure of a calcium-binding 63-kDa bone protein

21 January 2018

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The mammalian calcium-binding protein, nucleobindin (CALNUC), is a Golgi resident protein

21 January 2018

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Purification of a novel B cell growth and differentiation factor associated with lupus syndrome

21 January 2018

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Calnuc, an EF-hand Ca(2+)-binding protein, is stored and processed in the Golgi and secreted by the constitutive-like pathway in AtT20 cells

21 January 2018

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Organization of the human gene for nucleobindin (NUC) and its chromosomal assignment to 19q13.2-q13.4.

21 January 2018

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Overexpression of CALNUC (nucleobindin) increases agonist and thapsigargin releasable Ca2+ storage in the Golgi

21 January 2018

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Effect on tumor cells of blocking survival response to glucose deprivation

21 January 2018

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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis

21 January 2018

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Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins

21 January 2018

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Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1

21 January 2018

1 reference

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A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

Nucleobindin is produced by bone cells and secreted into the osteoid, with a potential role as a modulator of matrix maturation

21 January 2018

1 reference

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Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein

21 January 2018

1 reference

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Calnuc, an EF-hand Ca(2+) binding protein, specifically interacts with the C-terminal alpha5-helix of G(alpha)i3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M705038200

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

21 January 2018

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Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M705038200

1 reference

3 August 2017

1 reference