(Q34612511)

3 August 2017

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title

Gene function in mouse embryogenesis: get set for gastrulation (English)

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3 August 2017

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Patrick P L Tam

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3 August 2017

David A F Loebel

series ordinal

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3 August 2017

publication date

27 March 2007

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3 August 2017

published in

Nature Reviews Genetics

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3 August 2017

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3 August 2017

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3 August 2017

page(s)

368-381

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Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

3 August 2017

cites work

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Oct-3/4 and Sox2 regulate Oct-3/4 gene in embryonic stem cells

31 March 2020

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Transcriptional regulation of nanog by OCT4 and SOX2.

31 March 2020

1 reference

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

31 March 2020

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The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development

31 March 2020

1 reference

Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells

31 March 2020

1 reference

Control of developmental regulators by Polycomb in human embryonic stem cells

31 March 2020

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

31 March 2020

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Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo

31 March 2020

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TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

31 March 2020

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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

31 March 2020

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Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

31 March 2020

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Requirement for Wnt3 in vertebrate axis formation

31 March 2020

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Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.

31 March 2020

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Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway

31 March 2020

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Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

31 March 2020

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Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells

31 March 2020

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GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo

31 March 2020

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Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein

31 March 2020

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Disabled-2 is a negative regulator of integrin alpha(IIb)beta(3)-mediated fibrinogen adhesion and cell signaling.

31 March 2020

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The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm

31 March 2020

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Differentiation of embryonic stem cells is induced by GATA factors

31 March 2020

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Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis

31 March 2020

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Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates

31 March 2020

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Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment

31 March 2020

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Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm

31 March 2020

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The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development

31 March 2020

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Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

31 March 2020

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Visceral endoderm mediates forebrain development by suppressing posteriorizing signals

31 March 2020

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Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3

31 March 2020

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Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

31 March 2020

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Disruption of early proximodistal patterning and AVE formation in Apc mutants

31 March 2020

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The mouse embryo autonomously acquires anterior-posterior polarity at implantation

31 March 2020

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Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm.

31 March 2020

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Regionalised signalling within the extraembryonic ectoderm regulates anterior visceral endoderm positioning in the mouse embryo

31 March 2020

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Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning

31 March 2020

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Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi

31 March 2020

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

31 March 2020

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Requirement for beta-catenin in anterior-posterior axis formation in mice

31 March 2020

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Generation of novel conditional and hypomorphic alleles of the Smad2 gene.

31 March 2020

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Nodal signalling in the epiblast patterns the early mouse embryo

31 March 2020

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Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

31 March 2020

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Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation

31 March 2020

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Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo

31 March 2020

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The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

31 March 2020

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

31 March 2020

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Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

31 March 2020

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BMP type II receptor is required for gastrulation and early development of mouse embryos

31 March 2020

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The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4.

31 March 2020

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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

31 March 2020

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Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1

31 March 2020

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The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice

31 March 2020

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Beta-catenin signaling marks the prospective site of primitive streak formation in the mouse embryo

31 March 2020

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Mesodermal cell displacements during avian gastrulation are due to both individual cell-autonomous and convective tissue movements

31 March 2020

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Dynamic morphogenetic events characterize the mouse visceral endoderm

31 March 2020

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Active cell migration drives the unilateral movements of the anterior visceral endoderm

31 March 2020

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Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching

31 March 2020

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Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm

31 March 2020

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Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development

31 March 2020

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FGF Signaling Regulates Mesoderm Cell Fate Specification and Morphogenetic Movement at the Primitive Streak

31 March 2020

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T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification.

31 March 2020

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Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

31 March 2020

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Cell movement during chick primitive streak formation

31 March 2020

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Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos

31 March 2020

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IFITM/Mil/Fragilis Family Proteins IFITM1 and IFITM3 Play Distinct Roles in Mouse Primordial Germ Cell Homing and Repulsion

31 March 2020

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A molecular programme for the specification of germ cell fate in mice

31 March 2020

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Angiomotin regulates visceral endoderm movements during mouse embryogenesis

31 March 2020

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Conserved requirement of Lim1 function for cell movements during gastrulation

31 March 2020

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Crosstalk between different adhesion molecules

31 March 2020

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Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation

31 March 2020

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Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK

31 March 2020

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Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation

31 March 2020

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Requirement for Lim1 in head-organizer function

31 March 2020

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Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast

31 March 2020

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Definitive endoderm of the mouse embryo: formation, cell fates, and morphogenetic function

31 March 2020

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Extraembryonic proteases regulate Nodal signalling during gastrulation

31 March 2020

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FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse

31 March 2020

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Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

31 March 2020

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Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.

31 March 2020

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Cell fate decisions within the mouse organizer are governed by graded Nodal signals

31 March 2020

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Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

31 March 2020

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Development of definitive endoderm from embryonic stem cells in culture

31 March 2020

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Efficient differentiation of human embryonic stem cells to definitive endoderm

31 March 2020

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Transcriptional regulation of the homeobox gene Mixl1 by TGF-beta and FoxH1.

31 March 2020

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EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1.

31 March 2020

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Synergistic interaction between Gdf1 and Nodal during anterior axis development

31 March 2020

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31 March 2020

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BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites

31 March 2020

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The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain

31 March 2020

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Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse

31 March 2020

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Wnt/beta-catenin signaling and body plan formation in mouse embryos

31 March 2020

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Diversity of germ layer and axis formation among mammals

31 March 2020

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A flattened mouse embryo: leveling the playing field

31 March 2020

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Hypoblast controls mesoderm generation and axial patterning in the gastrulating rabbit embryo

31 March 2020

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The hypoblast of the chick embryo positions the primitive streak by antagonizing nodal signaling

31 March 2020

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Determination of embryonic polarity in a regulative system: evidence for endogenous inhibitors acting sequentially during primitive streak formation in the chick embryo

31 March 2020

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A role for the hypoblast (AVE) in the initiation of neural induction, independent of its ability to position the primitive streak

31 March 2020

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

31 March 2020

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Global expression analysis of gene regulatory pathways during endocrine pancreatic development.

31 March 2020

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Isolation of novel cDNAs by subtractions between the anterior mesendoderm of single mouse gastrula stage embryos

31 March 2020

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The in vitro morphogenesis of the guinea pig egg cylinder

31 March 2020

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Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst

31 March 2020

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Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

31 March 2020

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Gastrula organiser and embryonic patterning in the mouse

31 March 2020

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Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm

31 March 2020

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Multiple roles for Nodal in the epiblast of the mouse embryo in the establishment of anterior-posterior patterning

31 March 2020

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The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway

31 March 2020

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Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG2084

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Dimensions Publication ID

3 August 2017

1023301342

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