(Q34540416)

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Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity

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2 August 2017

Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity (English)

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2 August 2017

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neural stem cell

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26

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Guo-Li Ming

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25

object named as

Hongjun Song

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Daniel R. Weinberger

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Daniel R Weinberger

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2 August 2017

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Zhexing Wen

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2 August 2017

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Dan Rujescu

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2 August 2017

Judith L. Rapoport

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Judith L Rapoport

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2 August 2017

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David St Clair

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2 August 2017

Kimberly M Christian

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Kimberly M Christian

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2 August 2017

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Joo Heon Shin

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2 August 2017

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Nam-Shik Kim

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Georgia Makri

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2 August 2017

author name string

Ki-Jun Yoon

1

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2 August 2017

Ha Nam Nguyen

2

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2 August 2017

Gianluca Ursini

3

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2 August 2017

Fengyu Zhang

4

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2 August 2017

David Nauen

8

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2 August 2017

Youngbin Park

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2 August 2017

Raeeun Chung

11

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2 August 2017

Eva Pekle

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2 August 2017

Ce Zhang

13

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2 August 2017

Maxwell Towe

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2 August 2017

Syed Mohammed Qasim Hussaini

15

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2 August 2017

Yohan Lee

16

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2 August 2017

Joel E Kleinman

19

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Thomas M Hyde

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2 August 2017

Gregory Krauss

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publication date

1 July 2014

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2 August 2017

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2 August 2017

15

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1

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2 August 2017

79-91

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2 August 2017

Patches of disorganization in the neocortex of children with autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

CNVs conferring risk of autism or schizophrenia affect cognition in controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Copy number variants are frequent in genetic generalized epilepsy with intellectual disability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

DISC1 genetics, biology and psychiatric illness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Induced pluripotent stem cells: the new patient?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

CNVs: harbingers of a rare variant revolution in psychiatric genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Rare CNVs and tag SNPs at 15q11.2 are associated with schizophrenia in the Han Chinese population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

CYFIP dependent actin remodeling controls specific aspects of Drosophila eye morphogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

A copy number variation morbidity map of developmental delay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Normalization of cortical gray matter deficits in nonpsychotic siblings of patients with childhood-onset schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Essential role for Abi1 in embryonic survival and WAVE2 complex integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Confirmed rare copy number variants implicate novel genes in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

beta1 integrin maintains integrity of the embryonic neocortical stem cell niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Advances in autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

The glial nature of embryonic and adult neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Large recurrent microdeletions associated with schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Rare chromosomal deletions and duplications increase risk of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Spindle regulation in neural precursors of flies and mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

WAVE2 is required for directed cell migration and cardiovascular development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Human brain malformations and their lessons for neuronal migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

Neurodevelopmental abnormalities in schizophrenia: insights from neuropathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

7 July 2018

p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase.

1 reference

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7 July 2018

Implications of normal brain development for the pathogenesis of schizophrenia

1 reference

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7 July 2018

Genetic counseling for susceptibility loci and neurodevelopmental disorders: the del15q11.2 as an example.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

27 October 2018

Sra-1 interacts with Kette and Wasp and is required for neuronal and bristle development in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

27 October 2018

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237009

27 October 2018

Arp3 is required during preimplantation development of the mouse embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/24996170

12 December 2020

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10.1016/J.STEM.2014.05.003

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Europe PubMed Central

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2 August 2017

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2 August 2017

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