(Q34457226)

2 August 2017

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title

BAC to the future: the use of bac transgenic mice for neuroscience research (English)

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2 August 2017

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Heintz N

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2 August 2017

language of work or name

English

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publication date

1 December 2001

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Nature Reviews Neuroscience

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

861-870

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Initial sequencing and analysis of the human genome

2 August 2017

cites work

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7 January 2021

The Sequence of the Human Genome

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7 January 2021

The role of the genome project in determining gene function: insights from model organisms

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7 January 2021

Size matters: use of YACs, BACs and PACs in transgenic animals

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Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome

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Exchanging partners: recombination in E. coli.

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A new logic for DNA engineering using recombination in Escherichia coli

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Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis

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Modification of human beta-globin locus PAC clones by homologous recombination in Escherichia coli

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A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA

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7 January 2021

Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome

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Hox codes and positional specification in vertebrate embryonic axes

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Patterning the vertebrate neuraxis

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Patterning the cranial neural crest: hindbrain segmentation and Hox gene plasticity

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A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

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Functional expression of a mammalian odorant receptor

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Epitope tagging: general method for tracking recombinant proteins

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Internal ribosome entry site biology and its use in expression vectors.

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Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS.

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Transgenic mice generated by pronuclear injection of a yeast artificial chromosome.

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A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

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Exploring gene function: use of yeast artificial chromosome transgenesis

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Functional identification of the mouse circadian Clock gene by transgenic BAC rescue

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Physical localization of the mesoderm development (mesd) functional region.

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Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus.

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Transgenic rescue of the tattered phenotype by using a BAC encoding Ebp

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Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

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7 January 2021

Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice

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The apolipoprotein(a) gene is regulated by sex hormones and acute-phase inducers in YAC transgenic mice.

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7 January 2021

BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin

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Visualization of alpha9 acetylcholine receptor expression in hair cells of transgenic mice containing a modified bacterial artificial chromosome

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Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2

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Virus-assisted mapping of neural inputs to a feeding center in the hypothalamus

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Imprinted expression of neuronatin from modified BAC transgenes reveals regulation by distinct and distant enhancers

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Analysis of calcium channels in single spines using optical fluctuation analysis

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mRNA localization in neurons: a multipurpose mechanism?

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Local protein synthesis and its role in synapse-specific plasticity

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Protein synthesis at synaptic sites on dendrites

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Mechanisms of synaptic vesicle exocytosis

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7 January 2021

The synaptic vesicle cycle revisited

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7 January 2021

Molecular machinery mediating vesicle budding, docking and fusion

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The structure of postsynaptic densities isolated from dog cerebral cortex: I. overall morphology and protein composition

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The structure of postsynaptic densities isolated from dog cerebral cortex: II. characterization and arrangement of some of the major proteins within the structure

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Signal-processing machines at the postsynaptic density

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7 January 2021

Mitochondria and apoptosis

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A strategy for the analysis of gene expression during neural development

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Molecular determinants for subcellular localization of PSD-95 with an interacting K+ channel

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A novel genetic system to detect protein-protein interactions

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Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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New advances in Drosophila provide opportunities to study gene functions

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

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Positional cloning of the mouse circadian clock gene

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The complete family of genes encoding G proteins of Caenorhabditis elegans

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7 January 2021

Insights from mouse models into the molecular basis of neurodegeneration

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7 January 2021

Glutamine repeats and neurodegeneration

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7 January 2021

Beyond the Qs in the polyglutamine diseases

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7 January 2021

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse

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7 January 2021

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

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7 January 2021

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

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7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

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7 January 2021

Tetracycline-regulated gene expression in the brain

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7 January 2021

Laser capture microdissection

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7 January 2021

Purification of Purkinje cells by fluorescence-activated cell sorting from transgenic mice that express green fluorescent protein

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7 January 2021

Visualizing an olfactory sensory map

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7 January 2021

Olfactory coding: revealing intrinsic representations of odors

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7 January 2021

Human placental alkaline phosphatase as a histochemical marker of gene expression in transgenic mice.

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7 January 2021

Defining brain wiring patterns and mechanisms through gene trapping in mice.

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7 January 2021

A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene

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7 January 2021

A genetic approach to trace neural circuits

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7 January 2021

Inducible genetic suppression of neuronal excitability

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7 January 2021

ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons.

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7 January 2021

Targeted attenuation of electrical activity in Drosophila using a genetically modified K(+) channel.

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7 January 2021

Genome linking with yeast artificial chromosomes

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7 January 2021

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

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7 January 2021

A new bacteriophage P1-derived vector for the propagation of large human DNA fragments

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7 January 2021

Identifiers

DOI

10.1038/35104049

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Dimensions Publication ID

2 August 2017

1049388109

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