(Q33828583)

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Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection

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29 July 2017

Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection (English)

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Barton F Haynes

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Mario Roederer

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Michael K P Liu

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Natalie Hawkins

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Sydeaka Watson

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Cynthia Gay

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Kara McGhee

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Ian Williams

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publication date

10 February 2011

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29 July 2017

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29 July 2017

e1001273

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29 July 2017

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Creative Commons CC0 License

10 February 2011

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0 references

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1 reference

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Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing

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28 July 2018

Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication

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Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination

1 reference

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In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells

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CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells

1 reference

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The immune response during acute HIV-1 infection: clues for vaccine development

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Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand

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Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

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28 July 2018

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

1 reference

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Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection

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Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point

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Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

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Reduced viral replication capacity of human immunodeficiency virus type 1 subtype C caused by cytotoxic-T-lymphocyte escape mutations in HLA-B57 epitopes of capsid protein

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Post-step modifications for research on HIV vaccines

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HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case-cohort analysis

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Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status

1 reference

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Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection

1 reference

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28 July 2018

CD8+ T cell efficacy in vaccination and disease

1 reference

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28 July 2018

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037354

28 July 2018

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

1 reference

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Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

1 reference

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In vivo fitness costs of different Gag CD8 T-cell escape mutant simian-human immunodeficiency viruses for macaques

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Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

1 reference

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

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Estimating Costs and Benefits of CTL Escape Mutations in SIV/HIV Infection

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Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

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The rational design of an AIDS vaccine

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

1 reference

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Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response

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Immune escape precedes breakthrough human immunodeficiency virus type 1 viremia and broadening of the cytotoxic T-lymphocyte response in an HLA-B27-positive long-term-nonprogressing child

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Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides

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Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

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Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope

1 reference

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Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

1 reference

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Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

1 reference

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

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HIV and SIV CTL escape: implications for vaccine design

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Quantifying the uncertainty in forecasts of anthropogenic climate change

1 reference

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Acute phase cytotoxic T lymphocyte escape is a hallmark of simian immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

Identification and characterization of HIV-1 CD8+ T cell escape variants with impaired fitness

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

HIV-1-specific IFN-gamma/IL-2-secreting CD8 T cells support CD4-independent proliferation of HIV-1-specific CD8 T cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

21 January 2018

A Mathematical Theory of Communication

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1001273

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Phenotype and function of human T lymphocyte subsets: consensus and issues

1 reference

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29 October 2018

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037354

29 October 2018

Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia

1 reference

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29 October 2018

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/21347345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/21347345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of expansion of epitope-specific T cell responses during primary HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21347345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-B molecules target more conserved regions of the HIV-1 proteome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21347345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1001273

1 reference

https://api.fatcat.wiki/v0/release/57zqmr262nfw5pmcjnmdlcodlm

30 July 2022

based on heuristic

mapped directly with Wikidata item

release_57zqmr262nfw5pmcjnmdlcodlm

1 reference

https://api.fatcat.wiki/v0/release/57zqmr262nfw5pmcjnmdlcodlm

30 July 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

https://api.fatcat.wiki/v0/release/57zqmr262nfw5pmcjnmdlcodlm

30 July 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

https://api.fatcat.wiki/v0/release/57zqmr262nfw5pmcjnmdlcodlm

30 July 2022

based on heuristic

mapped directly with Wikidata item

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