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Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2.
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
main subject
DNA damage
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author
M Scott
series ordinal
4
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Helfrid Hochegger
series ordinal
5
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
David A Gillespie
series ordinal
6
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Nadia Hégarat
series ordinal
2
object named as
Nadia Hegarat
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Naihan Xu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Elizabeth J Black
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
language of work or name
English
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publication date
2 August 2010
1 reference
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Journal of Cell Biology
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
190
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Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
297-305
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stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51.
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Phosphoinositide 3-kinase signaling overrides a G2 phase arrest checkpoint and promotes aberrant cell cycling and death of hematopoietic cells after DNA damage.
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Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
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ATR: an essential regulator of genome integrity
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ATR signaling can drive cells into senescence in the absence of DNA breaks
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AKT/PKB signaling: navigating downstream
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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
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Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
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Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracil.
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Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects
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21 June 2018
DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway.
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21 June 2018
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
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21 June 2018
Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.
1 reference
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Crossref
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21 January 2018
A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Identifiers
DOI
10.1083/JCB.201003004
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMC publication ID
2922641
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
20679434
1 reference
stated in
Europe PubMed Central
PMC publication ID
2922641
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20679434%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
ResearchGate publication ID
45461573
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