(Q28613162)

3 February 2017

title

HLA-DM acts as a molecular chaperone and rescues empty HLA-DR molecules at lysosomal pH (English)

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3 February 2017

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H. Kropshofer

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3 February 2017

S. O. Arndt

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3 February 2017

G. Moldenhauer

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3 February 2017

G. J. Hämmerling

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3 February 2017

A. B. Vogt

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3 February 2017

language of work or name

English

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publication date

1 March 1997

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3 February 2017

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3 February 2017

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3 February 2017

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3 February 2017

page(s)

293–302

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In vivo and in vitro formation and dissociation of HLA-DR complexes with invariant chain-derived peptides

3 February 2017

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7 January 2021

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

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7 January 2021

Mapping functional regions in the lumenal domain of the class II-associated invariant chain

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7 January 2021

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

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7 January 2021

Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments

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7 January 2021

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

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7 January 2021

New class II-like genes in the murine MHC.

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7 January 2021

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

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7 January 2021

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

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7 January 2021

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7 January 2021

HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

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7 January 2021

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

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7 January 2021

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

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7 January 2021

Kinetics of intracellular transport and sorting of lysosomal membrane and plasma membrane proteins

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7 January 2021

Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells

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7 January 2021

A new human HLA class II-related locus, DM

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7 January 2021

Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

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7 January 2021

Self and foreign peptides interact with intact and disassembled MHC class II antigen HLA-DR via tryptophan pockets

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7 January 2021

Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding

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7 January 2021

Self-release of CLIP in peptide loading of HLA-DR molecules

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7 January 2021

How HLA-DM edits the MHC class II peptide repertoire: survival of the fittest?

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7 January 2021

Invariant chain targets HLA class II molecules to acidic endosomes containing internalized influenza virus

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7 January 2021

The MHC class II molecule H2-M is targeted to an endosomal compartment by a tyrosine-based targeting motif

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7 January 2021

Purification and characterization of human lysosomal membrane glycoproteins

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7 January 2021

Endosomal aspartic proteinases are required for invariant-chain processing

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7 January 2021

Transient aggregation of major histocompatibility complex class II chains during assembly in normal spleen cells.

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7 January 2021

A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments.

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7 January 2021

Characterization of peptides bound to extracellular and intracellular HLA-DR1 molecules

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7 January 2021

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

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7 January 2021

HLA-DM is localized to conventional and unconventional MHC class II-containing endocytic compartments.

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7 January 2021

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

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7 January 2021

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

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7 January 2021

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

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7 January 2021

Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

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7 January 2021

A role for peptide in determining MHC class II structure

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7 January 2021

MHC class II function preserved by low-affinity peptide interactions preceding stable binding

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Association between HLA-DM and HLA-DR in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Mediation by HLA-DM of dissociation of peptides from HLA-DR

1 reference

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7 January 2021

HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Isolation and characterization of the intracellular MHC class II compartment.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Selective release of some invariant chain-derived peptides from HLA-DR1 molecules at endosomal pH

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Human histocompatibility leukocyte antigen (HLA)-DM edits peptides presented by HLA-DR according to their ligand binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Mice lacking the MHC class II-associated invariant chain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

Enhanced dissociation of HLA-DR-bound peptides in the presence of HLA-DM

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980332-5

7 January 2021

10.1016/S1074-7613(00)80332-5

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017