(Q28510938)

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Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice

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scholarly article

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PubMed publication ID

25 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice (English)

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

cerebral infarction

1 reference

based on heuristic

inferred from title

Mitogen-activated protein kinase 3

1 reference

GOA release 2020-03-11

Superoxide dismutase 1, soluble

1 reference

GOA release 2020-03-11

Mitogen-activated protein kinase 1

1 reference

GOA release 2020-03-11

0 references

1 reference

based on heuristic

inferred from title

author name string

Nobuo Noshita

1

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Taku Sugawara

2

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Takeshi Hayashi

3

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Anders Lewén

4

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Ghezal Omar

5

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Pak H Chan

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

language of work or name

0 references

publication date

1 September 2002

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Journal of Neuroscience

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

22

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

18

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

7923-7930

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Apoptosis: Ras to the rescue in the fly eye.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytosolic antioxidant copper/zinc-superoxide dismutase prevents the early release of mitochondrial cytochrome c in ischemic brain after transient focal cerebral ischemia in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear mitogen-activated protein kinase activation by protein kinase czeta during reoxygenation after ischemic hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MAPK signaling cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of Mitogen‐Activated Protein Kinase in Cultured Rat Hippocampal Neurons by Stimulation of Glutamate Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of p42 Mitogen‐Activated Protein Kinase by Glutamate Receptor Stimulation in Rat Primary Cortical Cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf meets Ras: completing the framework of a signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain infarction is not reduced in SOD-1 transgenic mice after a permanent focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase signal transduction pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidants in ischemic brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raf revealed in life-or-death decisions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras signalling and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12223545

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-18-07923.2002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

PubMed publication ID

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12223545%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

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