(Q24654933)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

A pilot open label, single dose trial of fenobam in adults with fragile X syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

E Berry-Kravis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

D Hessl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

S Coffey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

C Hervey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

J Yuhas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

J Hutchison

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

M Snape

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

M Tranfaglia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

D V Nguyen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

R Hagerman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

6 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

Journal of Medical Genetics

19 January 2020

published in

1 reference

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19 January 2020

volume

1 reference

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19 January 2020

issue

1 reference

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19 January 2020

page(s)

266-271

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

Correction of fragile X syndrome in mice.

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Altered synaptic plasticity in a mouse model of fragile X mental retardation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The mGluR theory of fragile X mental retardation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The fragile X prevalence paradox

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Characterization of potential outcome measures for future clinical trials in fragile X syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Effect of CX516, an AMPA-modulating compound, on cognition and behavior in fragile X syndrome: a controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The relationship between sensorimotor gating and clinical improvement in acutely ill schizophrenia patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Local protein synthesis and spine morphogenesis: Fragile X syndrome and beyond.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Behavioural equivalents of anxiety in children with fragile X syndrome: parent and teacher report.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

The effects of methylphenidate on prepulse inhibition during attended and ignored prestimuli among boys with attention-deficit hyperactivity disorder.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658751

28 November 2018

Identifiers

DOI

10.1136/JMG.2008.063701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

19126569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19126569%20AND%20SRC:MED&resulttype=core&format=json