(Q24642376)

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IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression

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IFN regulatory factor 8 sensitizes soft tissue sarcoma cells to death receptor-initiated apoptosis via repression of FLICE-like protein expression (English)

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apoptotic process

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Andrea Hayes-Jordan

10

object named as

Andrea Hayes-Jordan

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object named as

Kebin Liu

14

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Alexander J. Lazar

object named as

Alexander Lazar

11

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author name string

Dafeng Yang

1

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Suizhao Wang

2

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Craig Brooks

3

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Zheng Dong

4

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Patricia V Schoenlein

5

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Vijay Kumar

6

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Xinshou Ouyang

7

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Huabao Xiong

8

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Guy Lahat

9

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Raphael Pollock

12

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Dina Lev

13

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language of work or name

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publication date

1 February 2009

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Cancer Research

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69

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3

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1080-8

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Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

7 April 2017

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

7 April 2017

Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene

1 reference

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7 April 2017

IFN regulatory factor 8 mediates apoptosis in nonhemopoietic tumor cells via regulation of Fas expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

7 April 2017

Repression of IFN regulatory factor 8 by DNA methylation is a molecular determinant of apoptotic resistance and metastatic phenotype in metastatic tumor cells

1 reference

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Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy

1 reference

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

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1 reference

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Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma

1 reference

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1 reference

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Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation

1 reference

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27 September 2017

CD95 stimulation results in the formation of a novel death effector domain protein-containing complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

27 September 2017

CD40 ligand protects from TRAIL-induced apoptosis in follicular lymphomas through NF-kappaB activation and up-regulation of c-FLIP and Bcl-xL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

27 September 2017

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

1 reference

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27 September 2017

Positive histone marks are associated with active transcription from a methylated ICSBP/IRF8 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

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The role of TRAIL death receptors in the treatment of hematological malignancies

1 reference

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The interferon consensus sequence-binding protein (ICSBP/IRF8) represses PTPN13 gene transcription in differentiating myeloid cells

1 reference

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27 September 2017

Host immunosurveillance controls tumor growth via IFN regulatory factor-8 dependent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

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Downregulation of IFN-gammaR in association with loss of Fas function is linked to tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2633427

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The feedback phase of type I interferon induction in dendritic cells requires interferon regulatory factor 8.

1 reference

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1 reference

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1 reference

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1 reference

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Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

1 reference

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1 reference

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Adult soft tissue sarcomas: conventional therapies and molecularly targeted approaches.

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Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages.

1 reference

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Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19155307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19155307

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19155307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-08-2520

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