Pages that link to "Q24339544"

The following pages link to Gain of interaction with IRS1 by p110α-helical domain mutants is crucial for their oncogenic functions (Q24339544):

Displaying 43 items.

• Insulin receptor substrate 1 (Q1665322) (← links)
• Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (Q7117823) (← links)
• Phosphoinositide-3-kinase regulatory subunit 1 (Q7119385) (← links)
• FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance (Q28077347) (← links)
• How do oncoprotein mutations rewire protein-protein interaction networks? (Q28087226) (← links)
• PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data (Q28247338) (← links)
• Hydrocarbon-stapled peptides: principles, practice, and progress (Q28542025) (← links)
• Analysis of individual protein regions provides novel insights on cancer pharmacogenomics (Q28542982) (← links)
• A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces (Q28550391) (← links)
• Targeting kinase signaling pathways with constrained peptide scaffolds (Q30398451) (← links)
• Activation of diverse signalling pathways by oncogenic PIK3CA mutations (Q34408364) (← links)
• A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations. (Q35155664) (← links)
• PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting (Q35260766) (← links)
• Novel Peptidomimetics for Inhibition of HER2:HER3 Heterodimerization in HER2-Positive Breast Cancer (Q35533514) (← links)
• Clinical Implications of Mutations in the PI3K Pathway in HER2+ Breast Cancer: Prognostic or Predictive? (Q36575502) (← links)
• Activation of IGF1R/p110β/AKT/mTOR confers resistance to α-specific PI3K inhibition. (Q36765341) (← links)
• The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR (Q37017948) (← links)
• Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer (Q37024512) (← links)
• Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells (Q37700992) (← links)
• Targeting the protein-protein interaction between IRS1 and mutant p110α for cancer therapy (Q38157714) (← links)
• Structure, function and inhibition of the phosphoinositide 3-kinase p110α enzyme (Q38180768) (← links)
• Correlation between PIK3CA mutations in cell-free DNA and everolimus efficacy in HR+, HER2- advanced breast cancer: results from BOLERO-2. (Q38376017) (← links)
• An enhanced functional interrogation/manipulation of intracellular signaling pathways with the peptide 'stapling' technology (Q38387363) (← links)
• PI3King the right partner: unique interactions and signaling by p110β. (Q38542387) (← links)
• PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity. (Q38716747) (← links)
• Designing helical peptide inhibitors of protein-protein interactions (Q38819761) (← links)
• Molecular Pathways: Targeting the PI3K Pathway in Cancer-BET Inhibitors to the Rescue (Q38850598) (← links)
• Neomorphic mutations create therapeutic challenges in cancer. (Q39007820) (← links)
• PI3K/AKT/mTOR: role in breast cancer progression, drug resistance, and treatment (Q39023175) (← links)
• Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis (Q41472107) (← links)
• Somatic mutations in arachidonic acid metabolism pathway genes enhance oral cancer post-treatment disease-free survival (Q41679141) (← links)
• Z-Selective olefin metathesis on peptides: investigation of side-chain influence, preorganization, and guidelines in substrate selection (Q42545827) (← links)
• Development and characterization of a colon PDX model that reproduces drug responsiveness and the mutation profiles of its original tumor. (Q44334484) (← links)
• Novel all-hydrocarbon stapled p110α[E545K] peptides as blockers of the oncogenic p110α[E545K]-IRS1 interaction (Q47402690) (← links)
• PI3K: A Crucial Piece in the RAS Signaling Puzzle (Q47894525) (← links)
• A novel allosteric site in casein kinase 2α discovered using combining bioinformatics and biochemistry methods (Q48022381) (← links)
• The COSMIC Cancer Gene Census: describing genetic dysfunction across all human cancers (Q57183712) (← links)
• Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast (Q57456357) (← links)
• The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer (Q60044742) (← links)
• Precision medicine - networks to the rescue (Q90560528) (← links)
• Signal Transduction Pathways in Breast Cancer: The Important Role of PI3K/Akt/mTOR (Q90640313) (← links)
• Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo (Q92025041) (← links)
• Challenges for the Clinical Development of PI3K Inhibitors: Strategies to Improve Their Impact in Solid Tumors (Q92339199) (← links)