(Q93270864)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

title

Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Matthew G Marzo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Jacqueline M Griswold

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

publication date

27 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

In vitro reconstitution of a highly processive recombinant human dynein complex

4 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Tyrosination of α-tubulin controls the initiation of processive dynein-dynactin motility

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Intraflagellar transport dynein is autoinhibited by trapping of its mechanical and track-binding elements

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The cryo-EM structure of intraflagellar transport trains reveals how dynein is inactivated to ensure unidirectional anterograde movement in cilia

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Single-molecule analysis of dynein processivity and stepping behavior

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 and dynein motor function in neuronal migration and development

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Systematic dissection of dynein regulators in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1, CLIP-170's key to the dynein/dynactin pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Dual subcellular roles for LIS1 and dynein in radial neuronal migration in live brain tissue

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 and NudE induce a persistent dynein force-producing state

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lissencephaly-1 is a context-dependent regulator of the human dynein complex

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Combinatorial regulation of the balance between dynein microtubule end accumulation and initiation of directed motility

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lis1 regulates dynein by sterically blocking its mechanochemical cycle

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Regulated offloading of cytoplasmic dynein from microtubule plus ends to the cortex

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Nudel/NudE and Lis1 promote dynein and dynactin interaction in the context of spindle morphogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Molecular basis for dyneinopathies reveals insight into dynein regulation and dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Microtubule-dependent path to the cell cortex for cytoplasmic dynein in mitotic spindle orientation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Insights into dynein motor domain function from a 3.3-Å crystal structure

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Crystal structure of the dynein motor domain

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Structure of human cytoplasmic dynein-2 primed for its power stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The affinity of the dynein microtubule-binding domain is modulated by the conformation of its coiled-coil stalk

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Molecular mechanism of cytoplasmic dynein tension sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Force-induced bidirectional stepping of cytoplasmic dynein

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Dynactin function in mitotic spindle positioning.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Motor- and tail-dependent targeting of dynein to microtubule plus ends and the cell cortex

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Myosin V orientates the mitotic spindle in yeast

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Spindle orientation in Saccharomyces cerevisiae depends on the transport of microtubule ends along polarized actin cables

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Asymmetric loading of Kar9 onto spindle poles and microtubules ensures proper spindle alignment

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Quantitative analysis of Pac1/LIS1-mediated dynein targeting: Implications for regulation of dynein activity in budding yeast

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Determinants of S. cerevisiae dynein localization and activation: implications for the mechanism of spindle positioning

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

NudEL targets dynein to microtubule ends through LIS1.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Lis1 activates dynein motility by modulating its pairing with dynactin

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Cryo-EM shows how dynactin recruits two dyneins for faster movement.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

LIS1 regulates cargo-adapter-mediated activation of dynein by overcoming its autoinhibition in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Short Synthetic Terminators for Improved Heterologous Gene Expression in Yeast

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The Phyre2 web portal for protein modeling, prediction and analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Novel mutations expand the clinical spectrum of DYNC1H1-associated spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Mutations in DYNC1H1 cause severe intellectual disability with neuronal migration defects.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

A chimeric kinesin-1 head/kinesin-5 tail motor switches between diffusive and processive motility

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Do zwitterions contribute to the ionic strength of a solution?

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Structural Basis for Microtubule Binding and Release by Dynein

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

Directionality of dynein is controlled by the angle and length of its stalk

1 reference

https://api.crossref.org/works/10.1038%2FS41556-020-0492-1

7 January 2021

10.1038/S41556-020-0492-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32341548%20AND%20SRC:MED&resulttype=core&format=json