(Q28362068)

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Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs

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Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs (English)

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Thomas E. Starzl

6

object named as

T E Starzl

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Anthony J. Demetris

7

object named as

A J Demetris

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John Julian Fung

5

object named as

J J Fung

1 reference

ORCID Public Data File 2021

author name string

J G Lunz

1

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S Contrucci

2

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K Ruppert

3

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N Murase

4

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language of work or name

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publication date

April 2001

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The American Journal of Pathology

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158

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4

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1379-90

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Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

FK506 and the role of the immunophilin FKBP-52 in nerve regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Ligand induced upregulation of the type II transforming growth factor (TGF-beta) receptor enhances TGF-beta responsiveness in COLO-357 cells

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: evidence for cooperation between p21Cip1/WAF1 and p27Kip1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

The Pittsburgh randomized trial of tacrolimus compared to cyclosporine for hepatic transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Characterization of biliary epithelial cells isolated from needle biopsies of human liver in the presence of hepatocyte growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Stimulation of transforming growth factor-beta 1 transcription by cyclosporine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Excretion of cyclosporine and its metabolites in human bile.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Isolation and primary cultures of human intrahepatic bile ductular epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Immunosuppressive effect of cyclosporine metabolites from human bile on alloreactive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

A histometric analysis of chronically rejected human liver allografts: insights into the mechanisms of bile duct loss: direct immunologic and ischemic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

FK 506 for liver, kidney, and pancreas transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

The relation of mesenchymal cell products to hepatic epithelial systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Conversion of liver allograft recipients from cyclosporine to FK 506-based immunosuppression: benefits and pitfalls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Pharmacokinetics of FK 506 following oral administration: a comparison of FK 506 and cyclosporine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Pharmacokinetics of FK 506: preclinical and clinical studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Conversion of liver allograft recipients from cyclosporine to FK506 immunosuppressive therapy--a clinicopathologic study of 96 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Cell Polyploidy: Its Relation to Tissue Growth and Function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

29 September 2017

Rethinking chronic allograft nephropathy: the concept of accelerated senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: implications for the development of obliterative bronchiolitis after lung transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Transforming growth factor-beta 1 stimulates or inhibits cell growth via down- or up-regulation of p21/Waf1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Regulation of new DNA synthesis in mammalian cells by cyclosporine. Demonstration of a transforming growth factor beta-dependent mechanism of inhibition of cell growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Cyclosporine stimulates expression of transforming growth factor-beta in renal cells. Possible mechanism of cyclosporines antiproliferative effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Determination of cyclosporine concentration in bile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Chronic liver allograft rejection and obliterative arteriopathy: possible pathogenic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Biopharmaceutical aspects of FK-506.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Chronic rejection after liver transplantation: a study of clinical, histopathological and immunological features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Vanishing bile-duct syndrome following liver transplantation--is it reversible?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

FK 506 used as rescue therapy for human liver allograft recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Proliferative Response of Smooth Muscle Cells in Hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

2 June 2018

Update of the International Banff Schema for Liver Allograft Rejection: working recommendations for the histopathologic staging and reporting of chronic rejection. An International Panel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

27 November 2018

Efficacy of tacrolimus as rescue therapy for chronic rejection in orthotopic liver transplantation: a report of the U.S. Multicenter Liver Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

27 November 2018

A Comparison of Tacrolimus (FK 506) and Cyclosporine for Immunosuppression in Liver Transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

27 November 2018

FK506 conversion for intractable rejection of the liver allograft.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891905

27 November 2018

Analysis of the reversibility of chronic liver allograft rejection implications for a staging schema

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Electron microscopy of rejected human liver allografts

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

High glucose induces a hypertrophic, senescent mesothelial cell phenotype after long in vivo exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

The effect of cyclosporin A and tacrolimus on cultured human epithelial cells: the role of TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

The effect of interleukin-6 (IL-6)/gp130 signalling on biliary epithelial cell growth, in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Use of human hepatocytes to study P450 gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Regulation of transforming growth factor-beta 1 and its receptor by cyclosporine in human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Regulation of cell cycle-related genes in rat hepatocytes by transforming growth factor beta1

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Apoptosis of bile duct epithelial cells in hepatic allograft rejection

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Apoptosis in the human liver during allograft rejection and end-stage liver disease

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Resistance to Fas-mediated apoptosis: activation of caspase 3 is regulated by cell cycle regulator p21WAF1 and IAP gene family ILP

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7 January 2021

Fas-mediated cholangiopathy in the murine model of graft versus host disease

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7 January 2021

Fibrosis in chronic rejection of human liver allografts: expression patterns of transforming growth factor-TGFbeta1 and TGF-beta3

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Rescue FK506 therapy for acute rejection and early chronic rejection after liver transplantation: report of 14 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice: interactions between the periductal inflammatory and stromal cells and the biliary epithelium

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

The immunosuppressant FK506 increases the rate of axonal regeneration in rat sciatic nerve

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Steroid receptors and heat-shock proteins in patients with primary biliary cirrhosis

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964089-8

7 January 2021

Ductular cell reaction in the liver in hepatic injury

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A induces transcription of transforming growth factor beta in a cultured murine proximal tubular cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/11290556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent cytomegalovirus in liver allografts with chronic rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11290556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events

1 reference

https://pubmed.ncbi.nlm.nih.gov/11290556

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/S0002-9440(10)64089-8

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