(Q37238575)

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Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium

scientific article published on 20 October 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Vasanthi R Muthusamy

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Sankaranarayanan Kannan

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kamal Sadhaasivam

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Sellamuthu S Gounder

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Christopher J Davidson

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Christoph Boeheme

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

John R Hoidal

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Li Wang

8

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Namakkal Soorappan Rajasekaran

9

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

20 October 2011

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Free Radical Biology and Medicine

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

52

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

366-376

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Reactive oxygen species in cardiovascular disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

NADPH oxidase and cardiac failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

When NRF2 talks, who's listening?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Stress-activated cap'n'collar transcription factors in aging and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Nrf2: friend or foe for chemoprevention?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Age-related changes in redox signaling and VSMC function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Nrf2:INrf2 (Keap1) signaling in oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

miRNA in the regulation of skeletal muscle adaptation to acute endurance exercise in C57Bl/6J male mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Age-associated oxidative damage to the p62 promoter: implications for Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Exercise improves import of 8-oxoguanine DNA glycosylase into the mitochondrial matrix of skeletal muscle and enhances the relative activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Production, detection, and adaptive responses to free radicals in exercise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Recent declines in chronic disability in the elderly U.S. population: risk factors and future dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Mechanisms of cardiovascular disease in accelerated aging syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Thioredoxin1 as a negative regulator of cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Oxidative stress and redox signalling in cardiac hypertrophy and heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Benefits of exercise for community-dwelling older adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Inhibition of endogenous thioredoxin in the heart increases oxidative stress and cardiac hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Mitochondrial free radical generation, oxidative stress, and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

New Aspects of Glutathione Metabolism and Translocation in Mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Glutathione: interorgan translocation, turnover, and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Glutathione and Related γ-Glutamyl Compounds: Biosynthesis and Utilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

6 September 2017

Dysfunctional Nrf2-Keap1 redox signaling in skeletal muscle of the sedentary old.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

14 September 2017

Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

14 September 2017

Cohort changes in active life expectancy in the U.S. elderly population: experience from the 1982-2004 National Long-Term Care Survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

14 September 2017

Glutathione, metabolism and function via the gamma-glutamyl cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

14 September 2017

Nrf2 protects against maladaptive cardiac responses to hemodynamic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

26 June 2018

The NADPH oxidase Nox4 and aging in the heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Redox imbalance influence in the myocardial Akt activation in aged rats treated with DHEA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

NADPH oxidase-derived superoxide impairs calcium transients and contraction in aged murine ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Free radicals and exercise: an introduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Nrf2, a multi-organ protector?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Chronic depletion of glutathione (GSH) and minimal modification of LDL in vivo: its prevention by glutathione mono ester (GME) therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Aging and Atherosclerosis: Changing Considerations in Cardiovascular Disease Prevention as the Barrier to Immortality is Approached in Old Age.

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3 September 2018

Aging or disease? Cardiovascular reactivity in Finnish men over the middle years.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Aging and cardiovascular disease: a summary of the Eighth Münster International Arteriosclerosis Symposium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3800165

3 September 2018

Aging and the prevalence of cardiovascular disease risk factors in older American Indians: the Strong Heart Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

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Selective modification of glutathione metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Testing the vicious cycle theory of mitochondrial ROS production: effects of H2O2 and cumene hydroperoxide treatment on heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of p27(kip1) contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial and skeletal muscle aging and changes in oxidative stress in relationship to rigorous exercise training

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiovascular disease and the aging U.S. population

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stanozolol treatment decreases the mitochondrial ROS generation and oxidative stress induced by acute exercise in rat skeletal muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubisemiquinone radicals in liver: implications for a mitochondrial Q cycle in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age and exercise-related changes in lipid peroxidation and superoxide dismutase activity in liver and soleus muscle tissues of rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

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The old-age heart: aging changes of the normal elderly heart and cardiovascular disease in 12 necropsy patients aged 90 to 101 years

1 reference

https://pubmed.ncbi.nlm.nih.gov/22051043

12 December 2020

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Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats

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https://pubmed.ncbi.nlm.nih.gov/22051043

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Identifiers

10.1016/J.FREERADBIOMED.2011.10.440

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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