(Q34328821)

1 August 2017

title

Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity (English)

1 reference

1 August 2017

1 reference

Rong-Jun Guo

1 reference

1 August 2017

Edward Huang

1 reference

1 August 2017

Toshihiko Ezaki

1 reference

1 August 2017

Neesha Patel

1 reference

1 August 2017

Kristen Sinclair

1 reference

1 August 2017

Jinling Wu

1 reference

1 August 2017

Peter Klein

1 reference

1 August 2017

Eun-Ran Suh

1 reference

1 August 2017

John P Lynch

1 reference

1 August 2017

language of work or name

English

0 references

publication date

23 June 2004

1 reference

Journal of Biological Chemistry

1 August 2017

1 reference

inferred from page(s)

published in

1 reference

1 August 2017

volume

279

1 reference

1 August 2017

1 reference

1 August 2017

page(s)

36865-36875

1 reference

The genetic basis of colorectal cancer: insights into critical pathways of tumorigenesis

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Molecular diagnosis of familial adenomatous polyposis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Linking colorectal cancer to Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Wingless-type frizzled protein receptor signaling and its putative role in human colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

A homeodomain protein related to caudal regulates intestine-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

An intestine-specific homeobox gene regulates proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Cdx1 promotes differentiation in a rat intestinal epithelial cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Colon carbonic anhydrase 1: transactivation of gene expression by the homeodomain protein Cdx2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Cdx1 inhibits the proliferation of human colon cancer cells by reducing cyclin D1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Post-transcriptional regulation of cyclin D1 expression during G2 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Cycling to cancer with cyclin D1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Beta-catenin/Tcf-regulated transcription prior to the midblastula transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Stimulation of Cdx1 by oncogenic beta-catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The competence of marginal zone cells to become Spemann's organizer is controlled by Xcad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The Xcad-2 gene can provide a ventral signal independent of BMP-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

naked cuticle encodes an inducible antagonist of Wnt signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The homeobox gene Cdx1 belongs to the p53-p21(WAF)-Bcl-2 network in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Identifying target genes regulated downstream of Cdx2 by microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Silencing of CDX2 expression in colon cancer via a dominant repression pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Cell type-specific autoregulation of the Caudal-related homeobox gene Cdx-2/3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

Beta-catenin mutations in cell lines established from human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405213200

21 January 2018

Identifiers

DOI

10.1074/JBC.M405213200

1 reference

1 August 2017

1 reference