Melfalan

Templat:Cs1 config

Melfalan

Nama sistematis (IUPAC)
4-[bis(2-Chloroethyl)amino]-L-phenylalanine
Data klinis
Nama dagang	Alkeran, Evomela, Phelinun, others
AHFS/Drugs.com	monograph
MedlinePlus	a682220
Data lisensi	US Daily Med:pranala
Kat. kehamilan	?
Status hukum	℞-only (US)
Rute	By mouth, intravenous, intra-arterial
Data farmakokinetik
Bioavailabilitas	25–89% (By mouth)
Metabolisme	Hydrolysis to inactive metabolites
Waktu paruh	1.5 ± 0.8 hours
Ekskresi	Kidney (IV: 5.8–21.3%)
Pengenal
Nomor CAS	148-82-3 Y
Kode ATC	L01AA03
PubChem	CID 460612
Ligan IUPHAR	7620
DrugBank	DB01042
ChemSpider	405297 Y
UNII	Q41OR9510P Y
KEGG	D00369 Y
ChEBI	CHEBI:28876 Y
ChEMBL	CHEMBL852 Y
Sinonim	(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid
Data kimia
Rumus	C13H18Cl2N2O2
InChI InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1 Y Key:SGDBTWWWUNNDEQ-LBPRGKRZSA-N Y

Melfalan adalah obat golongan agen antineoplastik sitotoksik. Melfalan bisa digunakan dalam tata laksana mieloma multipel seperti, kanker payudara, karsinoma ovarium, polisitemia vera, adenokarsinoma ovarium lanjut, melanoma, sarkoma jaringan lunak, atau neuroblastoma.^[1]