We find that about 5% of disease-associated mutations may affect known modification sites, either partially (4%) of fully (1%), compared to about 2% of�...
People also ask
What are the diseases resulting from failure of post-translational modification?
What is post-translational modification in disease?
What are post-translational modification sites?
Why is post-translational modification necessary?
We find that about 5% of disease-associated mutations may affect known modification sites, either partially (4%) of fully (1%), compared to about 2% of�...
In particular, we study the loss of modification target sites as a consequence of disease mutation. We find that about 5% of disease-associated mutations may�...
Feb 12, 2024 � In neurodegenerative diseases, several proteins undergo abnormal post-translational modifications, which leads to aggregation and abnormal deposition of�...
We find that about 5% of disease-associated mutations may affect known modification sites, either partially (4%) of fully (1%), compared to about 2% of�...
We find that about 5% of disease-associated mutations may affect known modification sites, either partially (4%) of fully (1%), compared to about 2% of�...
Sep 26, 2024 � Various post-translational modifications (PTMs) participate in nearly all aspects of biological processes by regulating protein functions, and�...
Jul 28, 2023 � How does post-translational modification affect cardiovascular disease? ... Myocardial infarction is a disease caused by a lack of energy�...
Missing: Loss | Show results with:Loss
Aug 20, 2021 � In this work, we hypothesized that the loss of specific protein functions defined by particular types of PTMs may map onto similar disease�...
A well-curated database containing PTMs that are associated with human diseases. We manually collected 1950 known PDAs in 749 proteins for 23 types of PTMs and�...
People also search for
