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Sep 30, 2021We propose to combine concepts of Parkinson's disease with the principle of complex object recognition.
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Parkinson's disease (PD) is a complex progressive neurodegenerative disease characterized by tremor, rigidity, and bradykinesia, with postural instability�...
Sep 4, 2024Parkinson's disease is a progressive movement disorder of the nervous system. It causes nerve cells (neurons) in parts of the brain to weaken, become damaged,�...
Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the substantia nigra.
The challenge of neurodegenerative diseases (ND) is an aging population. The second after Alzheimer's most common ND Parkinson's disease (PD) is�...
Feb 21, 2023The identified mechanisms of PD include α-synuclein aggregation, oxidative stress, ferroptosis, mitochondrial dysfunction, neuroinflammation, and gut dysbiosis.
Oct 25, 2017In this review, we provide a comprehensive overview of the current understanding of the molecular signaling pathways involved in PD.
Mar 20, 2019This Review will discuss key clinical features of PD and their basis in neural circuit dysfunction. We will first review important disease symptoms.
Sep 28, 2023An enterprising Cleveland Clinic research project aims to identify the specific neural dynamics that underlie PD movement disruptions.
Aug 14, 2023Parkinson's symptoms occur because of a drop in dopamine levels when certain brain cells die. Scientists know that abnormal clumping of certain�...