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Memory requirements #129

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gevro opened this issue Apr 17, 2024 · 1 comment
Open

Memory requirements #129

gevro opened this issue Apr 17, 2024 · 1 comment

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@gevro
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gevro commented Apr 17, 2024

Hi,
MuSiC is crashing with a single-cell reference of ~120k cells and 36 bulk samples due to memory limitations, even with 128 Gb RAM.

What are the memory requirements?

Thanks
@gevro
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gevro commented Apr 18, 2024

Note, it seems that high memory and time requirements are being caused specifically by the # of cells in the single-cell reference. I can analyze with up up to ~500 cells, but anything more than that takes > 30 minutes and eventually crashes due to out of memory even with 128 Gb ram.

Is there something I am missing in terms of how to run this?
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