Phentermine: Difference between revisions
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'''Phentermine''' is a drug that was part of the [[Fen-phen]] anti-[[obesity]] drug, the other drug being [[fenfluramine]]. Fenfluramine was withdrawn from the [[United State|U.S.]] market in [[1997]] after reports of [[heart valve disease]] and [[pulmonary hypertension]]. |
'''Phentermine''' is a drug that was part of the [[Fen-phen]] anti-[[obesity]] drug, the other drug being [[fenfluramine]]. Fenfluramine was withdrawn from the [[United State|U.S.]] market in [[1997]] after reports of [[heart valve disease]] and [[pulmonary hypertension]]. |
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Phentermine is still available by itself in most countries, including the U.S. Internationally, phentermine is a Schedule IV drug under the [[Convention on Psychotropic Substances]][http://www.incb.org/pdf/e/list/green.pdf]. |
Phentermine is still available by itself in most countries, including the U.S. Internationally, phentermine is a Schedule IV drug under the [[Convention on Psychotropic Substances]][http://www.incb.org/pdf/e/list/green.pdf]. |
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Phentermine, like many other prescription drugs, work with [[neurotransmitter]]s in the brain. It stimulates [[neuron]] bundles to release a particular group of neurotransmitters known as [[catecholamine]]s; these include [[dopamine]], [[epinephrine]] (formally known as adrenalin), and [[norepinephrine]] (noradrenalin). They signal a [[fight-or-flight response]] |
Phentermine, like many other prescription drugs, work with [[neurotransmitter]]s in the brain. It stimulates [[neuron]] bundles to release a particular group of neurotransmitters known as [[catecholamine]]s; these include [[dopamine]], [[epinephrine]] (formally known as adrenalin), and [[norepinephrine]] (noradrenalin). They signal a [[fight-or-flight response]] |
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Revision as of 19:25, 22 June 2005
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| IUPAC name: 1,1-Dimethyl-2-phenylethylamine | |
| CAS number |
122-09-8 |
| Chemical formula | C10H15N |
| Molecular weight | 149.2 |
| Bioavailability | ? |
| Metabolism | hepatic |
| Elimination half-life | ? |
| Excretion | ? |
| Pregnancy category | ? (United States) ? (Australia) |
| Legal status | C-IV (US) |
| Route of administration | Oral |
| Indicated for: |
Phentermine is a drug that was part of the Fen-phen anti-obesity drug, the other drug being fenfluramine. Fenfluramine was withdrawn from the U.S. market in 1997 after reports of heart valve disease and pulmonary hypertension.
Phentermine is still available by itself in most countries, including the U.S. Internationally, phentermine is a Schedule IV drug under the Convention on Psychotropic Substances[1].
Phentermine, like many other prescription drugs, work with neurotransmitters in the brain. It stimulates neuron bundles to release a particular group of neurotransmitters known as catecholamines; these include dopamine, epinephrine (formally known as adrenalin), and norepinephrine (noradrenalin). They signal a fight-or-flight response in your body which, in turn, puts a halt to the hunger signal. As a result, you lose your appetite because your brain doesn’t receive the hunger message. This is perhaps due to phentermine’s affects on leptin levels in the brain. It is theorized that phentermine can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This chemical initiates eating, decreases energy expenditure, and increases fat storage.