Butalbital: Difference between revisions
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| IUPAC_name = ''5-(2-methylpropyl)-5-(2-propenyl)-<BR>2,4,6(1''H'',3''H'',5''H'')-pyrimidinetrione'' |
| IUPAC_name = ''5-(2-methylpropyl)-5-(2-propenyl)-<BR>2,4,6(1''H'',3''H'',5''H'')-pyrimidinetrione'' |
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| image = Butalbital.png |
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| excretion = ? |
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| pregnancy_category = ? |
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| legal_US = Schedule III |
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| routes_of_administration = ? |
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{{cite web | title=Butalbital and Acetaminophen (Systemic) | work=MedicinePlus Drug Information | url=http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202102.html | accessdate=December 31 | accessyear=2006}} |
{{cite web | title=Butalbital and Acetaminophen (Systemic) | work=MedicinePlus Drug Information | url=http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202102.html | accessdate=December 31 | accessyear=2006}} |
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{{Barbiturates}} |
{{Barbiturates}} |
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Revision as of 19:32, 13 January 2007
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| Clinical data | |
|---|---|
| Pregnancy category |
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| Routes of administration | ? |
| Legal status | |
| Legal status |
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| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Elimination half-life | about 35 hours[1] |
| Excretion | ? |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| DrugBank | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.000.926 |
| Chemical and physical data | |
| Formula | Template:Carbon11Template:Hydrogen16Template:Nitrogen2Template:Oxygen3 |
| Molar mass | 224.256 |
Butalbital, 5-allyl-5-isobutylbarbituric acid, is a barbiturate with an intermediate duration of action. It has the same chemical formula as talbutal but a different structure. Butalbital is often combined with other medications, such as acetaminophen or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA approved for the treatment of tension headaches.
Combinations include:
- butalbital and acetaminophen (Axocet®, Bucet®, Bupap®, Cephadyn®, Dolgic®, Phrenilin®, Phrenilin Forte®, Sedapap®)
- butalbital, acetaminophen, and caffeine (Fioricet®, Esgic®, Esgic-Plus®)
- butalbital and aspirin (Axotal®)
- butalbital, aspirin, and caffeine (Fiorinal®, Fiormor®, Fiortal®, Fortabs®, Laniroif®)
- butalbital, acetaminophen, caffeine, and codeine phosphate (Fioricet #3 with Codeine®) (Fioricet w/ Codeine®)
- butalbital, aspirin, caffeine, and codeine phosphate (Fiorinal #3 with Codeine®) (Fiorinal w/ Codeine®)
Side effects
Side effects for any drug are difficult to predict, but commonly reported side effects for Butalbital include:
- Dizziness
- Drowsiness
- Intoxicated feeling
- Light-headedness
- Nausea
- Sedation
- Addiction
- Severe impairment of judgement
There are other potential side effects, this list should not be considered all-inclusive.
Dangers and Risks
Butalbital is a physically and psychologically addictive barbituate. Butalbital should not be mixed with alcohol due to increased risk of intoxication.
There are other potential risks, this list should not be considered all-inclusive.
External links
"Butalbital". On-line Medical Dictionary. Retrieved June 26. {{cite web}}: Check date values in: |accessdate= (help); Unknown parameter |accessyear= ignored (|access-date= suggested) (help)
"Butalbital and Acetaminophen (Systemic)". MedicinePlus Drug Information. Retrieved December 31. {{cite web}}: Check date values in: |accessdate= (help); Unknown parameter |accessyear= ignored (|access-date= suggested) (help)
"Controlled Substances in Schedule III". Drug Enforcement Agency. 2007. Retrieved 2007-01-13.
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- ^ "Egsic Plus". National Institutes of Health. 2002. Retrieved 2006-12-24.