Steroid-induced osteoporosis: Difference between revisions

'''Steroid-induced osteoporosis''' (SIOP) is [[osteoporosis]] arising due to use of [[glucocorticoid]]s - analogous to [[Cushing's syndrome]] and involving mainly the axial skeleton. The synthetic glucocorticoid prescription drug [[prednisone]] is a main candidate after prolonged intake. Some professional guidelines recommend prophylaxis in patients who take the equivalent of more than 30&nbsp;mg hydrocortisone (7.5&nbsp;mg of prednisolone), especially when this is in excess of three months.<ref name="Bone2003">{{cite book |author=Bone and Tooth Society of Great Britain, [[National Osteoporosis Society]], Royal College of Physicians |title=Glucocorticoid-induced Osteoporosis |year=2003 |publisher=Royal College of Physicians of London |location=London, UK |isbn=1-860-16173-1 | url=http://www.rcplondon.ac.uk/pubs/contents/966c62dd-8011-4f65-a61d-dd0c7fe4fa4b.pdf}}</ref> Alternate day use may not prevent this complication.<ref name=GIOP>{{cite journal|author=Gourlay M, Franceschini N, Sheyn Y| title=Prevention and treatment strategies for glucocorticoid-induced osteoporotic fractures |journal=Clin Rheumatol| year=2007|volume=26|issue=2|pages=144–53|pmid=16670825 |doi=10.1007/s10067-006-0315-1}}</ref>