doi: 10.1038/ncb0908-1021.
Twisted epithelial-mesenchymal transition blocks senescence
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- PMID: 18758491
- DOI: 10.1038/ncb0908-1021
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Twisted epithelial-mesenchymal transition blocks senescence
Nat Cell Biol.
2008 Sep.
Abstract
The epithelial-mesenchymal transition (EMT) is a cellular transdifferentiation program that enables epithelial cancer cells to acquire traits of high-grade malignancy, notably invasive and metastatic powers. A new study indicates that it may also function early in tumour progression by preventing oncogene-induced senescence.
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