When Bernadette's hair is cut off she has some blood on her face. Not nearly as much as the close up of her with blood running down her face and caked on around her eyes.
In the beginning, a man plays a Taylor acoustic guitar. Taylor Guitars was established in 1974.
When Margaret's brother shows up to take his sister home, he not only knows his way around the facility, but knows exactly which room everyone is in, despite having never set foot in the place.