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A smart alecky San Francisco, California cop and his get rich quick scheme of a partner keep tabs on crime and take down the bad guys in the Bay Area.

After young policewoman Gina Pulasky succeeds in handling a domestic fight particularly well, she's added to a small team of detectives assigned to a case of gruesome child killings. She proves herself to be a worthwhile reinforcement by tracking down the prime suspect, a disturbingly smart young man named Kyle Timler. Much to the horror of her team mate and lover Will McCaid, Pulasky goes undercover to infiltrate in Timler's life and trying to get as close to him as necessary to make him confess his crimes without even noticing it. A dangerous mission involving a process of growing identification with the killer, something that doesn't leave Pulasky unscathed.

As Joe gets Nash's "Cuda" detailed secretly, as a Christmas present, it is stolen, much to his despair. Meanwhile, the rest of the SIU team are stuck at the precinct on Christmas Eve until they wrap up a murder investigation.

Just as Nash plans to go on a belated honeymoon with Kelly, a very important case lands on his desk. Nash must locate San Francisco's most notorious bookie and rogue FBI officer who happens to be number 9 on the FBI's 10 most wanted list.

A serial killer's victim appears to be Nash's mysterious friend, Angel (Tracey Walter); Harvey has a reunion with his estranged wife.

A hard-nosed Internal Affairs advocate (Yasmine Bleeth) is on the case when Nash and Joe are accused of murdering three cops.

An old acquaintance of Nash and Joe, a Canadian cop, is on the run from Canada and on the hunt in the U.S. for a couple of bad guys. Nash has McCabe write Cassidy's 20-week probation report. Nick has troubles with another pier fisherman that gets blown way out of proportion.

Nash has to figure out the details of his undercover operation after he loses his short term memory because of an explosion.

Nash and the S.I.U look into the world of battle bots and their builders to find out who's using their bots to rob convenience stores and armored cars. Dominguez thinks he's found an original copy of The Declaration of Independence.

Rick Bettina escapes from prison with the help of an old foe of Nash's, leading on a hunt for him and the missing money. Joe has to deal with his contractor and his architect having a big fight and splitting.

Nash's former love is involved in the theft of plutonium. He has to fight the Fed's, Pakistani gunmen and his own feelings to stop her.

A sleepless Nash and company stop a disgruntled bomber from further retaliation against his software employer. Cassidy performs topless in a play, but an unknowing Nash falls asleep.

Harvey is enjoying a night out at a benefit concert when two beautiful young women use a front end loader to bust through the wall and then make off with all the proceeds on a custom Harley motorcycle. The S,I,U tracks them down.

Cassidy and McCabe walk in on a bank robbery and shoot it out with the perpetrators. One of the customers is killed, but it's unclear who's gun the fatal shot came from and Cassidy is suspended pending an inquiry.

Nash pursues the disturbed brother of a dead cop, who uses the uniform to take law into his own hands and just plain take from people. Nick tries to get a driver's license.

Nash and company discover a gang of female bank robbers who plan to break their husbands out of jail. Nick schemes to move into a formerly all-women retirement home. Caitlin readies her negative report on the SIU, much to Nash's consternation.

A prisoner facing a parole hearing sets up a bounty website to have Nash killed in order to avoid Nash keeping him locked away after the hearing. Nash worries that Cassidy's new boyfriend who she's serious about, may be playing for the other team.

Nash and the SIU discover the Cell Phone Killer's intentions are to kill his doctor. Lonely Joe keeps having erotic dreams about Caitlin. Evan gets fired from his bartender job.

A deadly carjacking leads Nash and the SIU team to a drug dealer who owns a Hemi Cuda similar to Nash's. Meanwhile, Evan and Richard Bettina enter a transgender beauty contest to catch a killer.

An embezzler with a twin, along with bumbling Rick Bettina, confound the efforts of Nash and the SIU to recover stolen city funds. Caitlin tosses Nash's baseball out the window after they miss their flight to Jamaica.

Nash and his SIU team search for the source of deadly VX nerve gas before there are catastrophic consequences. Meanwhile, things heat up between Cassidy and Evan, and a young woman believes that Joe might be her father.

Nash and Joe have to deal with some nasty ex-military types who have been killing drug dealers and taking their money. Joe's nervous about his baby being born. Nash finds an old letter his ex-wife wrote him dated the day of their divorce.

A prisoner being delivered for execution is kidnapped in a plot that may involve the British consulate. Joe tries to get his daughter into a prestigious daycare business.

Nash and Joe find not only themselves but their private investigators business impersonated. Harvey finds himself as the deciding vote in the neighborhood over a contentious issue. Cassidy investigates the supposed accidental death of a young college man.

Bettina, upon learning that Nash has nearly a year's worth of vacation time, tells him to take it. In the meantime he brings in a new guy to fill in, and he starts by investigating a murder with Joe. Nash tries to find a way to get back.